A compound that inhibit the aromatase enzyme from creating estrogen is called an aromatase inhibitor or AI for short. There are a lot of options out there when it comes to AI's (aromatase inhibitors) and GP Exemestane is certainly one of the most popular options for bodybuilders that cycle steroids for a number of reasons.Aromasin is a suicidal aromatase inhibitor, which makes it a better choice than other AIs. GP Exemestane binds with aromatase enzymes and then subsequently permanently disables the enzyme by destroying it.
GP Exemestane is a steroidal AI which keeps it from negatively affecting your lipids like other non-steroidal AIs. It is also not liver toxic, and can be ran for longer lengths of time without negative effect. This makes it a better option to run on cycle from a pure health standpoint. GP Exemestane will not hurt your gains on cycle like other aromatase inhibitors, but may actually help them. Another benefit on cycle is that steroidal AIs lower SHBG which increases the ratio of free to bound testosterone. What that means during your cycle is a very positive impact on your gains. This (in a sense) makes your anabolic androgenic steroids more bio-available.
The half-life of GP Exemestane is only about 9 hours, and clears quickly. However, because of how effective GP Exemestane is at eliminating aromatase enzymes (80-90% after administration), estrogen levels will remain low up to 72 hours after a single dose of 25mg. This is why GP Exemestane is very effectively dosed every other day. In one study, users were still 40% below baseline estrogen values 72 hours after their dose. This makes GP Exemestane very versatile for dosing and not require more frequency.
Now, the place where GP Exemestane really shines is in post cycle therapy (PCT). There is simply no other aromatase inhibitor that can compare in terms of its effects on recovery. We already mentioned how Aromasin lowers SHBG, which increases free testosterone. What does that mean? In a study, Aromasin dosed at 25mg per day increased total testosterone by 60% in only 10 days. Even better than that, is the fact that free (useable) testosterone increased over 100% in the same time frame! In addition, GP Exemestane also increases IGF-1 levels. There is no estrogen rebound from GP Exemestane , and it is also a very powerful and effective treatment for gynecomastia. All of this makes GP Exemestane a no-brainer for post cycle therapy as well as on cycle estrogen control.