Tuesday, February 24, 2015

Dianabol and use in bodybuilding

Dianabol, an orally-effective anabolic steroid. An extremely popular steroid among athletes and bodybuilders, this performance enhancing drug is readily available without a prescription in many countries.

Dianabol has the ability of stimulating dramatic and nearly-permanent improvements in terms of muscle strength, muscle function and size, glycogenolysis, and protein synthesis. This anabolic androgenic steroid can easily pass through the liver and only a small part of this steroid gets broken down because of 17α-methylation of Dianabol. This means Dbol can even be used by athletes who are prone to liver toxicity when using oral steroids.

This steroid has been extremely popular among amateur and professional
bodybuilders and some of the most eminent names to have accepted its use include Arnold Schwarzenegger, Ronnie Coleman and Phil Heath. Dianabol is best used at the start of a steroid cycle to kick start gains and may even be used as a bridge between steroid cycles for maintaining muscle mass and body strength gains.
Dianabol is a fast-acting anabolic steroid which works quickly and quite effectively on the body. Depending upon the desired effects, athletes, weightlifters and power lifters will have a wide dosage range with Dianabol.  The daily dose range, depending upon the individual can range anywhere from 2-20 tablets per day, though an effective dose for athletes would be around 15-40 mg per day. One reason that Dianabol is preferred for use in athletes is because of the medications ability to reduce endogenous cortisone levels by as much as 50-70%, which slows the rate of protein breakdown in the muscles.

This steroid is rated a better option (gram for gram) than Testosterone as Dianabol minimizes affinity of the steroid for sex hormone binding globulin, which is a protein deactivating steroid molecules and capable of inhibiting them from further reactions in the body. In addition to this, Dianabol remains the favorite choice among power lifters and bodybuilders as it helps them increase repetitions during intense workouts and reduces workout fatigue to a significant extent. This steroid also has the ability to promote the sense of well being and sleep patterns. Dianabol use is also associated with the promotion of calcium deposits in the bones, improving bone strength, and enhancing muscle density while improving endurance capacity.

Recommended Dose Of Dianabol:
Male athletes usually use Dianabol in doses of 25-50mg every day while female athletes prefer using Dianabol in doses of 10-20mg every day. Dbol is ideally stacked with Primobolan, Deca Durabolin, Trenbolone Acetate, Testosterone enanthate or propionate and Deca Durabolin. Athletes administered with Dianabol should always emphasize on post cycle therapy with Clomid and Nolvadex. This is important for restoring the production of natural testosterone in the body and preventing excess estrogen formation that could have resulted in estrogenic side effects like oily skin, gynecomastia, and acne.

Dianabol is not recommended to those diagnosed with health conditions such as hypertension, high blood pressure, and prostate or breast cancer. It is also not advised to those diagnosed with health conditions such as testicular atrophy, testicular cancer, liver damage, kidney damage, stroke, or respiratory problems. It is also not recommended for children and girls and women, especially those who are pregnant, breastfeeding, or who may get pregnant while using it. Dianabol is also not advised to those who are allergic to it's ingredients.

This potent anabolic steroid should not be overdosed in hopes of quick benefits. The use of Dianabol over extended periods of time should always be avoided as it may lead to liver damage in case of qualified knowledge or lack of appropriate care. Moreover, it should always be purchased from a reputed steroid pharmacy with a valid medical prescription. Abuse or overdosing or use of low grade Dianabol can lead to side effects like male pattern baldness, clitoral hypertrophy, oily skin bouts, and insomnia or difficulty when urinating, edema (swelling), increased aggression, fever, or pain in the lower back (particularly in the kidney areas), and high blood pressure. Dianabol capsules, pills, or injections should be discarded by taking the advice of a pharmacist or local waste disposal company in case they are not to be used any more or expired.

Dianabol has both strong anabolic and androgenic action which means a noticeable increase in strength, force and muscle mass.  With the medication users can expect an increase of 1-2 kg of weight per week, which during the first 6 weeks of usage is normal. With the dosage of Dianabol being varied, particularly among trainees, weight lifters and athletes, the medication dosage may fluctuate between 2-10 pills per day and in some cases higher.  The effects on weightlifters can be most noticed at a dosage between 15-40 mg per day.

For the beginning weight trainer, the dose should never be higher than 15-25 mg per day, this dosage is effective to yield noticeable results within an 8-10 week continuous cycle.  If the steroidal effects of Dianabol are decreased after an 8-week cycle, the medication can be used in conjunction with another injectable steroid, but the dose does not need to be increased.

For a weightlifter, good results can be obtained at a dosage of 20-30 mg per day of Dianabol combined with an additional 200-400 mg dose of Deca-Durabolin weekly.  For those who seek a strength increase and muscular definition, combing Dianabol with Oxandrolone or Winstrol, will yield desirable results.

Dianabol is not recommended for competition weight training because it causes significant water retention.  Women who wish to use Dianabol can experience desirable results at a dosage of 10-20 mg per day.  For women who do not experience any adverse side effects from using Dianabol, a dosage of 2-4 pastilles a day for a period of 4-6 weeks can be ideal.Though Dianabol has many adverse side effects, but are rare for athletes who take a dose of 20 mg per day.  The main side long-term side effect of Dianabol is liver damage, which can be experienced at both high and low doses.

Dianabol: Cycle

Dianabol has an active life of between 6-8 hours, with a half-life of around 3-4 hours.  A single daily dose of Dianabol will produce a varying blood level, with fluctuations experienced throughout the day.  A person can take a dose in whole form or split up the tablets during the day, by dividing up the dose the user will be better able to control blood concentration levels. An average dose of Dianabol for males is between 15-50 mg per day and for women between 5-10 mg per day. Being the preferable steroid for men, even a moderate amount of Dianabol will result in extreme masculinizing characteristics in women.

Thursday, February 19, 2015

T3 and T4 - the two effective thyroid hormones

Hypothyroidism is a condition classified by an under-active thyroid gland—when the thyroid does not produce enough hormones. There are various treatments available, but the basic concept is the same—and it's known as thyroid hormone replacement therapy.
To best understand the purpose of thyroid hormone replacement therapy, you need to understand the interaction of T3 and T4—the two thyroid hormones. Both the thyroid and parathyroid glands are endocrine glands. This means they make and secrete (release) hormones. Hormones are chemicals which can be released into the bloodstream. They act as messengers, affecting cells and tissues in distant parts of your body. Thyroid hormones affect the body's metabolic rate and the levels of certain minerals in the blood. The hormone produced by the parathyroid also helps to control the amount of these essential minerals.

The full name of T3 is Triiodothyronine and T4's full name is Tetraiodothyronine or Thyroxine. T3 and T4 control your body's metabolism. If you don't have enough of them, then your metabolism slows down. Your metabolic rate dictates how quickly you process food, how fast your heart beats, how much heat your body creates—and even how quickly you can think. In essence, T3 and T4 are in charge of how your body uses energy.
T3 and T4 are not equal in strength; T3 is the more active hormone of the two. While T3 is stronger, taking synthetic T4 hormone is considered the standard treatment for hypothyroidism. The reason for this is because most of the T3 in our bodies actually used to be T4. When T4 hormones come into contact with other cells in the bloodstream, they give up an iodine atom to interact with those cells. When T4 loses an iodine atom, it becomes T3.

When this T4 into T3 conversion occurs, T3 then conveys the metabolic "message" to the other cells throughout the body. The benefit of taking only T4 therapy is that you're allowing your body to perform some of the actions it is meant to do, which is taking T4 and changing it into T3. The half life of T4 is also longer compared to T3 (7 days versus 24 hours), that means that it will stay for a longer time in your body after ingestion.

The thyroid makes three hormones that it secretes into the bloodstream. Two of these hormones, called Thyroxine (T4) and Triiodothyronine (T3), increase your body's metabolic rate. Essentially, the body's metabolic rate is how quickly the cells in your body use the energy stored within them. Thyroid hormones make cells use more energy. By controlling how much energy our cells use, thyroid hormones also help to regulate our body temperature. Heat is released when energy is used, increasing our body temperature. Thyroid hormones also play a role in making proteins, the building blocks of the body's cells. They also increase the use of the body's fat and glucose stores.

In order to make T3 and T4, the thyroid gland needs iodine, a substance found in the food we eat. T4 is called this because it contains four atoms of iodine. T3 contains three atoms of iodine. In the cells and tissues of the body most T4 is converted to T3. T3 is the more active hormone, it influences the activity of all the cells and tissues of your body.

The other hormone that the thyroid makes is called calcitonin. This helps to control the levels of calcium and phosphorus in the blood. These minerals are needed, among other things, to keep bones strong and healthy. Your thyroid gland is a small gland, normally weighing less than one ounce, located in the front of the neck. It is made up of two halves, called lobes, that lie along the windpipe (trachea) and are joined together by a narrow band of thyroid tissue, known as the isthmus. The function of the thyroid gland is to take iodine, found in many foods, and convert it into thyroid hormones: Thyroxine (T4) and Triiodothyronine (T3). Thyroid cells are the only cells in the body which can absorb iodine. These cells combine iodine and the amino acid tyrosine to make T3 and T4. T3 and T4 are then released into the blood stream and are transported throughout the body where they control metabolism (conversion of oxygen and calories to energy).

Every cell in the body depends upon thyroid hormones for regulation of their metabolism. The normal thyroid gland produces about 80% T4 and about 20% T3, however, T3 possesses about four times the hormone "strength" as T4. The thyroid gland is under the control of the pituitary gland, a small gland the size of a peanut at the base of the brain (shown here in orange). When the level of thyroid hormones (T3 and T4) drops too low, the pituitary gland produces Thyroid Stimulating Hormone (TSH) which stimulates the thyroid gland to produce more hormones. Under the influence of TSH, the thyroid will manufacture and secrete T3 and T4 thereby raising their blood levels. The pituitary senses this and responds by decreasing its TSH production. One can imagine the thyroid gland as a furnace and the pituitary gland as the thermostat.

The pituitary gland itself is regulated by another gland, known as the hypothalamus (shown in the picture above in light blue). The hypothalamus is part of the brain and produces TSH Releasing Hormone (TRH) which tells the pituitary gland to stimulate the thyroid gland (release TSH). One might imagine the hypothalamus as the person who regulates the thermostat since it tells the pituitary gland at what level the thyroid should be set.

Treatment of hypothyroidism:
After proper diagnosis of hypothyroidism, the next issue is with what substance to treat. The traditional approach is to use Synthroid/ Levoxyl/Levothroid (levothyroxine) which is only T4. Natural medicine doctors tend to use Armour thyroid which is a mixture of mono and di-iodothryonine and T3 and T4, the entire range of thyroid hormones.

If the Free T3 level is significantly lower than the Free T4 level, it is next to useless to treat with Synthroid/ Levoxyl/Levothroid (T4) only replacements. If the patient could not muster sufficient T3 from their gland (which produces some T3 directly), then they are certainly not going to convert enough T3 from T4 only. Traditional medicine assumes that preparations like Synthroid which are T4 only converts peripherally in the body to T3 in fairly standard amounts and at fairly standard rates. Unfortunately, clinical experience shows this is not true for the majority of patients. Consistent measuring of both free T3 and free T4 blood levels in hypothyroid patients who are on T4 only therapy will very rapidly dispel this myth. A certain percentage of hypothyroid patients do convert enough T4 to T3 at a sufficient rate for T4 treatment to be adequate as a source of T3; but a substantial proportion of patients require some combination of both exogenous T3 and T4.

Once on hormone replacement, the TSH remains useful until it goes BELOW 0.4. Then one has optimized thyroid function by the TSH yardstick; it then remains to optimize thyroid function by the yardstick of the accurate measures of the 2 thyroid hormones, the Free T4 and Free T3 levels.

So one should use a combination of T4 and T3 which compensates for the inability to convert T4 to T3. This is most frequently done with Armour thyroid. However, Cytomel, which is T3 only, can be used in combination with one of the T4 only preparations. It is important to recognize that T3 should always be prescribed twice daily due to its shorter half life. This is typically after breakfast AND supper for compliance reasons.

Taking the dose at these times overcomes traditional medicine's major objection and resistance to using natural thyroid preparations - its variability in its blood levels. Armour thyroid is desiccated thyroid and has both T3 and T4. Most doctors using Armour thyroid are not aware that Armour thyroid should be used twice daily and NOT once a day. The major reason is that the T3 component has such a short half life and needs to be taken twice daily to achieve consistent blood levels.

Once or twice daily dosing one can then optimize both the T4 and T3 levels, with whatever thyroid preparation is required. This is not possible in most hypothyroid patients with T4 only preparations. It is important to use a preparation with T3 because T3 does 90% of the work of the thyroid in the body. The only exception to pursue optimization of the T3 level without using Armour thyroid is in severe acute cardio-pulmonary conditions, when the metabolic slowing effect of a low FT3 level can actually be life-saving. However, the vast majority of hypothyroid patients do not have acute cardio-pulmonary conditions, such as congestive heart failure.

The most common starting dose for patients with hypothyroidism is Armour thyroid, 90 mg which is cut in half with a razor blade and half is taken after breakfast and the other half after dinner. Taking it after meals also helps to reduce volatility of the blood-level of T3. If the patient has any problem breaking or cutting the pill, they should purchase a pill-cutter at the pharmacy. The TSH, Free T3 and Free T4 are then repeated in one month and the dose is adjusted.

In order to optimize the hormone replacement, the Free T3 and Free T4 should be above the median but below the upper end of the laboratory normal reference range. The goal for healthy young adults would be to have numbers close to the upper part of the range, and for cardiace and/or elderly patients, the numbers should be in the middle of its range. The Free T3 and Free T4 levels should be checked every month and the hormone therapy readjusted until the FT3 and FT4 levels are in the therapeutic range described. A small number of large, overweight, thyroid-resistant women may need 6-8 grains of Armour Thyroid or the equivalent of thyroxine per day (counting 0.1mg of T4 as 1 grain of Armour Thyroid). Patients need to be warned about the overdosage symptoms which are frequently only temporary during the adaptation stage. The symptoms may include: palpitations, nervousness, feeling hot and sweaty, rapid weight-loss, fine tremor, and clammy skin. There is one exception to the 1.5 level of TSH as the cutoff for treatment. Overweight patients who have classic symptoms of hypothyroidism and have made heroic unsuccessful attempts to lose weight may benefit from thyroid hormone replacement even if their TSH slightly below 1.5 and FT4 and FT3 are not below their normal ranges. Since the only change will be in the FT3 level, which has a short half-life, the serum FT4 and FT3 levels (and TSH, if indicated) can be measured 48-72 hrs after the splitting of the doses if the patient had been on the hormone for 4-6 weeks before the splitting of the doses. This is because the T4 fraction is the one that takes a number of weeks to build up to its steady-state serum level.

Wednesday, February 11, 2015

The classic Anadrol 50/Sustanon 250 cycle for build muscles

Anadrol 50 and Sustanon 250 are both excellent mass weight and strength gain drugs. Though each is androgenic and anabolic in nature, both have high estrogenic activity potential (though through different mechanisms). This means that each can dramatically suppress the natural testosterone production regulated by the body’s HPTA (hypothalamus-pituitary-testes-axis) system due to the negative feed-back loop caused by too much estrogen in a males body. Interestingly enough is the fact that the same estrogenic activity has a profound positive effect upon the amount of weight and strength gain an individual will realize during the administration of either or both of these drugs.

Sustanon 250 is a commonly prescribed drug for treating low testosterone levels in men (TRT). This steroid compound is used by athletes and bodybuilders to gain muscle mass and increase strength.

Also known as Dura-Testin, Sustoplex and Sustanon, this anabolic androgenic steroid is a blend of four components of Testosterone — Testosterone propionate 30 mg, Testosterone decanoate 100 mg, Testosterone phenylpropionate 60 mg, and Testosterone isocaproate 60 mg and the total amount of testosterone per mL of Sustanon is 250mg.

During testing, Sustanon 250 can be detected over a period of 2-3 months, and has an active life of approximately 2-3 weeks. Use of this steroid is also associated with development and maintenance of reproductive tissues such as prostate, epidermis, seminal vesicles, testes, and the male sexual organ even at low doses. Athletes and bodybuilders use Sustanon 250 as it improves oxygen carrying capacity of the body and promotes muscle function, muscle size,  strength, performance, stamina, and red blood cell production.

Estrogens in any form trigger glucose up-take by some tissues. In this case the tissue of interest is muscle and the result is greater levels of glycogen and water stored inside of the muscle cell. The benefits are rather obvious but bare mentioning none the less. Increased glycogen means increased fuel in the cells to make our favorite muscle gasoline called ATP (Adenosine Tri-Phosphate). This provides for an increase in training intensity and faster post-training recovery. Each gram of glycogen synthesized and stored brings with it about 3 grams of water. This adds to the cells structural integrity like putting a foundation under a house. With a stronger foundation comes a greater load capacity. Big weights and extra fuel will ultimately increase muscle mass and allow for bigger weights. One factor positively effects the other.

Anabolics increase protein synthesis in muscle tissue and androgen's aid the process while increasing training intensity. A greater weight and work-load from increased training intensity results in a greater stimulus to the trained muscles that tells it to adapt by getting stronger and bigger. However without the anabolic effect that tells the muscle fibers to grow… nothing happens. So the combination of a high androgenic drug with an anabolic substance will result in growth, but the addition of one that has estrogenic activity (by way of structure like AD-50 or aromatization like testosterones) will fuel the process at a greater rate.

Sounds great but the problem is the cycle exit and the set of raisins swinging comically down stairs post-cycle. Remember the HPTA? The excess estrogen shuts down natural testosterone production from "the boys" in a time progressive manner. This means that as the cycle or protocol continues the inhibition of the HPTA grows greater. With the resulting lack of natural androgen production post-cycle the male body finds itself in an estrogen dominant environment that in itself destroys male attributes. Yes, this does include the newly acquired muscle mass as well.

The Anadrol 50 and Sustanon 250 stack will result in a rapid weight and strength gains that will be lost post-cycle due to HPTA shut-down. Sustanon has about a 21 day active-life. But since it is made up of 4 different testosterone esters, each with different active-lifes, the period of build-up and decline of actual testosterone in the circulatory system requires an administration schedule intended to allow for this. In short, as one begins to run out the next replaces it after the dosage peaks. AD-50 has an active-life of less than 16 hours so it is easily scheduled to act as a replacement androgen for the shorter acting testosterone esters in Sustanon. The result is a fairly stable androgen activity level and the ability to keep the HPTA functioning nearer to normal. Additionally this allows for improved post-cycle lean mass retention if an athlete continues to train and eat properly. There has of course been better choices for this type of protocol and the specific intended application bares a reason for discussion as well.

100 tabs of Anadrol 50 mg, 14 x 2 ml Sustanon 250 mg, 4 x 1 ml vial of HCG 5000 u.i., 40 tabs of Nolvadex 20 mg.

This is the classic Anadrol/Test stack. If you are looking for sheer mass, you are not going to find a better mix. Be warned though, estrogenic side effects are likely to be intense. A super cycle for mass building with strong anabolics like Anadrol and Sustanon. A cycle resulting in the highest mass gains and stronger androgen properties

Friday, February 6, 2015

Powerful anabolic steroid Drostanolone Propionate

Masteron is a modified form of Dihydrotestosterone, with a methyl group at the 2nd carbon (carbon alpha) atom. This modification is responsible for the anabolic strength increase. This methyl group makes it harder for the enzyme 3-hydroxysteroid dehydrogenase to metabolize Masteron. This enzyme is abundantly present in muscle tissue, and is responsible for degrading any DHT into two inactive metabolites: 3-Alpha Androstanediol and 3-Beta Androstanediol. Because of this enzyme DHT is not anabolic in muscle tissue at all. It is believed that if the enzyme 3-hydroxysteroid dehydrogenase was neutralized, DHT would actually be a very powerful anabolic steroid. Drostanolone's methyl group addition makes it imune to this enzyme. 

Drostanolone is injected into the body as an ester (bonded to either Propionate or Enanthate). Enzymes cleave off the ester from the Masteron molecule - which takes varying amount of time depending on which ester was used. This process causes the gradual release rate and extended half-life of the steroid. Drostanolone Propionate has a half-life of 2.5 days, while Drostanolone Enanthate has a half-life of 10 days. 

Intended use of Drostanolone / Masteron:  
Masteron was initially marketed as a treatment of female breast cancer. Because it pronounced male characteristics in women and because more effective breast cancer treatments were invented, Drostanolone was gradually phased out.

Actual use of Masteron:
Nowadays Drostanolone is a very popular anabolic steroid used mainly by athletes and bodybuilders.

Like other steroids Masteron can be injected into any muscle (if the muscle is big enough). The most popular being buttocks, shoulders and triceps. 

Masteron cycle compatibility, examples and duration 

Like majority of steroids, Masteron acts very well in combination with Human Growth Hormone (4IU per day). 

Effects of Drostanolone / Masteron (desirable) 

There are principally two desirable effects of Testosterone: 
physical / athletic performance enhancement (endurance, strength, faster regeneration)  physique enhancement (muscle buildup, fat loss)
The rest of desirable testosterone effects that an individual might experience during the steroid cycle, include:  increase in collagen synthesis and bone mineral content. Collagen is the protein-based construction material for connective tissues throughout the body (the ligaments, tendons, cartilage, joints, and bones).

Masterone or Drostanolone is an anabolic androgenic steroid that has been successfully used as a breast cancer drug. This anabolic androgenic steroid is commonly used by athletes who want to retain strength and muscle mass while losing fat. Also used in the bodybuilding community as a muscle defining drug and diuretic, this steroid can increase muscle hardness and density in a short period of time to give a more complete appearance to users, when preparing for bodybuilding contests. 

Masteron is available in two forms: Masteron propionate and Masteron enanthate. The primary difference between these two is that while the enanthate version is slow but long acting, the propionate version is fast and is required to be injected every other day.

Masteron propionate (or Drostanolone propionate) is perhaps one of the more "exotic" anabolic androgenic steroids in today's online market. It can be purchased, with or without a medical prescription, in different forms like capsules, tablets, sprays, or injections. Masteron propionate has a half life of 1-2 days.

Commonly used as a cutting or pre-contest drug, its use is associated with improvements in terms of aggression, performance, stamina, muscle size, and muscle function. This derivative of Dihydrotestosterone (DHT) blocks the conversion of free testosterone to estrogen by the aromatization pathway by inhibiting the aromatase enzyme. As a result, Masteron marginally increases the amounts of active free testosterone in circulation and negate the side effects of high estrogen levels because of aromatization.

One of the biggest advantages associated with use of this steroid is that it promotes strength gains while keeping body fat the same or even lowering it to prevent muscle loss while dieting. This advantage proves extremely advantageous for athletes in sports that have weight classes to improve performance, without the risk of being raised into a higher weight class. Masteron, an excellent cutting steroid, has recently become very popular in the underground market due to its efficacy and safety quotients compared to other steroids on sale.

Undoubtedly one of the most popular bodybuilding steroids of all time, Drostanolone Propionate has the ability to reduce estrogen in the body to a great extent. This steroid has a dramatic hardening effect on a lean physique and promotes greater metabolic activity and is most effective when used by athletes already in a lean state or when the level of body fat is already low. Masteron does not aromatize in the first place but may weaken the aromatase effect of many other anabolic steroids. Masteron inhibits water retention and athletes and bodybuilders using this drug can feel tight and very full after using it to experience "muscle pumps" like never before in the gym. In addition to these advantages, Masteron is also useful to accentuate fine details of muscles like striations.

The recommended dose of Masteron propionate for men is 500-700mg every week. This steroid is best stacked with Anadrol, Testosterone propionate, Dianabol, and Trenbolone acetate. This anabolic steroid may be stacked with Clenbuterol, Ephedrine, T3, Winstrol, and even Growth hormone or IGF-1. 

Masteron enanthate, which is also known as Drostanolone enanthate, has the chemical name of 17beta-Hydroxy-2alpha-methyl-5alpha-androstan-3-one Enanthate. This steroid has an active life of nearly eight to nine days and can be detected for up to several weeks. It has an anabolic androgenic rate of 62:25.

This steroid provides an aesthetic enhancement effect and is considered by bodybuilders as one of the best steroids to reduce any possible subcutaneous water retention that may obscure the view of muscle mass underneath. It also enhances bioavailability of other steroids in an anabolic steroid cycle through its anti-estrogen and anti-aromatase effects and preventing a measurable amount of SHBG (Sex Hormone Binding Globulin) from binding to other anabolic steroids and rendering them inactive. This anabolic androgenic steroid is best used for its ability to inhibit the transformation of free testosterone to estrogen and thereby enhancing the rate of free testosterone circulating in the body. The recommended dosage of Masteron enanthate is 400-600 mg weekly for men and 100 mg weekly for females and can be stacked with Trenbolone Enanthate, Clenbuterol, Ephedrine, T3, IGF-1, and Testosterone.

Masteron, available in oral and injectable forms, is not recommended to those suffering from health problems like testicular atrophy, testicular cancer, prostate cancer, breast cancer, liver damage, kidney damage, stroke, high blood pressure, and respiratory problems. The use of Masteron enanthate or propionate is also not advised for girls and women, especially who are pregnant, breastfeeding, or may get pregnant while using it. It is also not advised for children or those diagnosed with hypertension, high blood pressure, and prostate or breast cancer or those treated for health conditions such as testicular atrophy, testicular cancer, liver damage, kidney damage, stroke, and respiratory problems.

When abused or overdosed, Masteron can lead to oily skin, acne, body/facial hair growth, deepening of the voice, and hair loss. It may even cause increased sebum secretion (oily skin), increased bouts of acne (associated with increased sebum secretion), bodily and facial hair growth, and the increased risk of male pattern baldness. In women, Masteron can cause side effects like development of male secondary sex characteristics such as deepening of the voice, growth of body and facial hair), clitoral enlargement, and menstrual irregularities. Abuse of this steroid can even lead to suppression of the HPTA (Hypothalamic Pituitary Testicular Axis) and natural endogenous Testosterone production. Therefore, the use of post cycle therapy drugs like Clomid or Nolvadex is highly recommended to restore the normalization of the HPTA and endogenous Testosterone production as quickly as possible.