Tuesday, September 23, 2014

Steroid cycles for novice

People who wish to cut fat and add muscles simultaneously and want to utilize legal and relieve drugs must confer with a dr. before using any anabolic steroid. The clip period in which a individual utilizes anabolic steroids is named anabolic steroid cycle. The steroid rounds can include also taking an anabolic steroid at the beginning of the cycle and finish with another steroid, to raise the wanted consequence.

Steroids, as synthetic versions of the testosterone, are stimulating the muscles development. Users will look strong and big on the outside, forgetting the side upshots, that may be creating failing inside.

Steroid stacks have turn uped to be the most efficient style to construct musculus than when the athlete utilizes one type. The utilize of more than one steroid in an anabolic steroid cycle is dramatically increasing the peril of side upshots. This is the ground why the steroids users will stack non-anabolic drugs to minimize the harmful steroid side upshots.

An anabolic steroid cycle is the period where a users uptakes this type of drugs. A long anabolic steroid cycle will really touch the hypothalamus / pituitary gland / testicular axis to bump. HPT suppression will do necessary a permanent testosterone therapy. Many steroid abusers are stacking drugs, cycling or pyramiding is defining the practice of gradually increasing and gradually decreasing anabolic steroid doses over a period if clip.

Steroid cycle continuance depend on the drug users. Some mortals are often against short rounds and long periods of time off; some are suggesting a old ages one shot utilize to have optimal issues. In reality, it is really up to the individual to take the cycle that lawsuits best for him. Tiroes must watch the consumption continuance because the anabolic steroids are strong. Easily aromatized steroids should be employed for only short intervals, less than eight weeks. After this period, it is necessary a interruption of at least as long as the previous period. The physical structure requires clip to bump and remainder.

The users who are not respecting these indicants must check up on often their wellness status. The fact that anabolic steroids are not acting dramatically is making some users to found the anabolic steroid cycle for a long clip period. The best solution is to construct the muscles tissues using traditional methods, such as preparation and appropriate diet.

Many athletes do not understand these prescriptions and bump a cycle of three or four months most appropriate. The athlete must avoid the utilize of steroids an old ages after a steroid cycle, in order to prize the natural hormonal balance. The physical structure really requires a clip to retrieve the natural hormonal balance. Someone must insure that there are only very little possibilities of future side upshots. If an individual believes that these upshots are reversible, they are wrong. Problems with libido, virility, sterility can look because the physical structure was overloaded with male internal secretions for years. Anabolic steroid rounds are involving high blood pressure level, liver toxicity, high cholesterol grades and athlete must throttle the continuance on anabolic steroid rounds if they are not avoiding it completely.

Friday, September 19, 2014

Peptides how they work and why would a player use them?

Peptides are a small chain of amino acids that isn’t quite long enough to be considered a full protein (less than 50 units). They are, in essence, the building blocks that create protein.

In a supplement form peptides come in different chemical compounds. The ones the ACC report identifies as being used within the Australian sporting community are known as GHRP-2, GHRP-6 and CJC-1295. IGF, MGF and SARMs are identified by the ACC as commonly used peptides used in the bodybuilding community. The next big question to consider is why an athlete would consider using peptides.

Peptides are used for their anabolic effect on an athlete’s muscle mass. (GHRP means growth hormone releasing hexapeptide, a type of growth hormone releasing hormone). This can be useful in a couple of ways.

Obviously an athlete will need to heal quickly and be productive soon after an injury. Peptides will help the muscle or soft tissue in this rebuilding healing process.

Supplements that provide an anabolic effect could also be used during preseason and other periods where building muscle mass is important.

Muscle mass can be built quickly because the athlete can make small tears in a muscle and have it heal on a rapid schedule to continuously repeat the process – the end effect being increased muscle mass and reduced body fat in a shorter time frame.

The bodybuilding community use peptides that are most effective in this second way as newer peptides don’t come with the side-effects of anabolic steroids.

It is the links to bodybuilding and gym communities that help pro-athletes find new substances such as peptides to improve performance.

For some time now, the bodybuilding community has been aware of these supplements and the inability for testing to detect them in most cases.

This is especially the case if urine testing is the main form of detection. Many peptides aren’t yet cleared for human use.

However, peptides are readily available on the sporting supplement market and aren’t very expensive.
They would have to be missing out on the biggest peptides boom in the history of the supplement industry with all the recent focus on their attributes.

Now we know what peptides are and what they can be used for.

The real issues are how many athletes have been using them and whether the ACC, ASADA and the police can catch the ones who have.

Tuesday, September 9, 2014

Effect of peptide hormone CJC-1295 in your body workout

CJC-1295 is basically a peptide hormone that acts similar to growth hormone releasing hormones (GHRH). It is beneficial to athletes because it can bioconjugate with circulating albumin and increase the time it can be used for medical purposes. It achieves this by preventing degradation of its amino acids. With a single dose, it can remain in the body for quite a few days and can cause the growth hormone to be released many times per day. This reduces the frequency of injections needed.CJC-1295 increases the production of growth hormone as well as IGF-1 – which has anabolic effects in adults. However, it does not increase the levels of prolactin – high levels of which can create impotence and mental health problems in men. By increasing these two hormones, it enhances protein production in the body, which in turn, boosts muscle mass. It also induces lipolysis – the breakdown of fat tissue, boosts recovery from injuries, increases bone density, and also reduces aging factors like skin wrinkles. It can also stimulate cell growth, due to which it can be used to treat withered tissue or organs.

CJC-1295 is also known by the names of Modified GRF 1-29, Mod GRF 1-29, CJC-1295 without DAC (DAC stands for Drug Affinity Complex) and also by its chemical name tetrasubstituted GRF (1-29). This variety of names makes it difficult for the average consumer to select or even research upon this compound. Since some manufacturers list all of its names and others list only one, it also becomes very confusing. However, there is a reason for this wide variety of names.

The original GRF (1-29) has a half-life of about 30 minutes. Half-life means the time within which half of the hormone administered will be destroyed within the body. This short half-life is due to the fact that the compound is highly unstable and breaks down soon. To increase its stability and to make it last longer, it was modified by adding 4 amino acids in its structure. This gave it the name Modified GRF (1-29) or Mod GRF 1-29. It was originally invented by DatBtrue. The portion of the molecule that actually stimulates the growth hormone secretion is found in the chain of 29 amino acids, so it is named GRF (1-29). This chemical also produces slow-wave sleep.

However, both the original GRF (1-29) and the Mod GRF 1-29 required frequent dosages. So a new compound called CJC-1295 was created which was far more stable. This compound was made by adding Lysine – which is a non-peptide, and is also called Drug Affinity Complex or DAC. Since the original Mod GRF 1-29 does not contain DAC, it is named as CJC-1295 without DAC. However, the actual CJC-1295 is not only difficult, but also very expensive to produce. This is why it is not produced or used extensively. The Mod GRF 1-29 is far easier and cheaper to produce. CJC-1295 acts for much longer than pure GRF. It acts on the pituitary gland and keeps stimulating the release of growth hormone in pulses. The reason why it acts in pulses is because the axis of the human growth hormone controls how much of the hormone can remain in the body at a time. This maintains the homeostatic environment in the body.

The DAC technology in the CJC-1295 enables the compound to bind itself covalently with any circulating albumin, after it has been administered through a subcutaneous injection. However, the reason why the half-life could be extended from a few minutes to several days is more profound. The reactive group in the CJC-1295 binds to a peptide through bioconjugation. The peptide then finds a neucleophilic unit within the blood and reacts with it in order to create a firmer bond.

When using any GHRH, it should always be remembered that positive results cannot be achieved overnight. These compounds act steadily over time, and the best results can be achieved slowly, and with a nutritious diet and a proper exercise regime. Also, these peptides are not sex-specific, so they do not have any androgenic effects. They can be used by women in the same dosages that men do. Mod GRF 1-29 and CJC-1295 are still being researched. As such, they are not yet medically utilized or approved. Though some firm protocols for the use of these peptides have been developed, the dosage of the compound is not yet medically confirmed. In a study conducted by researchers on 21 to 61 year-old subjects, it was found that depending on the dose, the concentrations of the growth hormone increased to up to 10 times for at least 6 days. Also, the concentration of IGF-1 increased to up to 3 times for 9 to 11 days.

CJC-1295 and Mod GRF 1-29 are administered in micrograms (mcg) rather than milligrams (mg) – the unit of administration of other steroids and performance-enhancing drugs. It has also been found that a 100mcg dose is enough to fully saturate the receptors in the anterior pituitary. This is called the saturation dose. After a dose of 100mcg has been administered, the subsequent dosages will achieve only half the effect.For example, if 100mcg more were to be administered after the first 100mcg (making the effective dose of 200mcg), then the second dose will achieve only 50% of what the first dose already did. A 100mcg more (making a total of 300mcg) will achieve only 25% more of the initial dose. This implies that, in order to increase the effect of the compound, only a little more of it can be successfully administered after the saturation dose.

Tuesday, September 2, 2014

Proviron (Mesterolone) effective anabolic steroid

Proviron (Mesterolone) an anabolic steroid, is particularly interesting. This drug has good binding to the androgen receptor, but in muscle tissue most of it never reaches the androgen receptor because it is enzymatically converted to the diol. Thus, it is not an effective anabolic. It is somewhat effective as an anti-gyno agent, however, and appears to reduce estrogenic bloating if that problem exists. Proviron reduces either levels of estrogen or the effect of estrogen. Thus, it is useful for avoiding gynecomastia, although it probably should not be relied upon as the sole drug for that. It is not hepatotoxic. It has the usual side effects of anabolic/androgenic steroids, with the added effect that it is particularly prone to cause erections.

Mesterolone is an orally active, 1-methylated DHT. Like Masteron, but then actually delivered in an oral fashion. DHT is the conversion product of testosterone at the 5-alpha-reductase enzyme, the result being a hormone that is 3 to 4 times as androgenic and is structurally incapable of forming estrogen. One would imagine then that Mesterolone would be a perfect drug to enhance strength and add small but completely lean gains to the frame. Unfortunately there is a control mechanism for DHT in the human body. When levels get too high, the 3alpha hydroxysteroid dehydrogenase enzyme converts it to a mostly inactive compound known as 3-alpha (5-alpha-androstan-3alpha,17beta-diol), a pro-hormone if you will. It can equally convert back to DHT by way of the same enzyme when low levels of DHT are detected. But it means that unless one uses ridiculously high amounts, most of what is administered is quite useless at the height of the androgen receptor in muscle tissue and thus Mesterolone is not particularly suited, if at all, to promote muscle hypertrophy.

Proviron has four distinct uses in the world of bodybuilding. The first being the result of its structure. It is 5-alpha reduced and not capable of forming estrogen, yet it nonetheless has a much higher affinity for the aromatase enzyme (which converts testosterone to estrogen) than testosterone does. That means in administering it with testosterone or another aromatizable compound, it prevents estrogen build-up because it binds to the aromatase enzyme very strongly, thereby preventing these steroids from interacting with it and forming estrogen. So Mesterolone use has the extreme benefit of reducing estrogenic side-effects and water retention noted with other steroids, and as such still help to provide mostly lean gains. Its also been suggested that it may actually downgrade the actual estrogen receptor making it doubly effective at reducing circulating estrogen levels.

The second use is in enhancing the potency of testosterone. Testosterone in the body at normal physiological levels is mostly inactive. As much as 97 or 98 percent of testosterone in that amount is bound to sex hormone binding globulin (SHBG) and albumin, two proteins. In such a form testosterone is mostly inactive. But as with the aromatase enzyme, DHT has a higher affinity for these proteins than testosterone does, so when administered simultaneously the mesterolone will attach to the SHBG and albumin, leaving larger amounts of free testosterone to mediate anabolic activities such as protein synthesis. Another way in which it helps to increase gains. Its also another part of the equation that makes it ineffective on its own, as binding to these proteins too, would render it a non-issue at the androgen receptor.

Thirdly, Mesterolone is added in per-contest phases to increase a distinct hardness and muscle density. Probably due to its reduction in circulating estrogen, perhaps due to the down regulating of the estrogen receptor in muscle tissue, it decreases the total water build-up of the body giving its user a much leaner look, and a visual effect of possessing "harder" muscles with more cuts and striations. Proviron is often used as a last-minute secret by a lot of bodybuilders and both actors and models have used it time and again to deliver top shape day in day out, when needed. Like the other methylated DHT compound, drostanolone, mesterolone is particularly potent in achieving this feat.

Lastly Proviron is used during a cycle of certain hormones such as nandrolone, with a distinct lack of androgenic nature, or perhaps 5-alpha reduced hormones that don't have the same affinities as DHT does. Such compounds, thinking of trenbolone, nandrolone and such in particular, have been known to decrease libido. Limiting the athlete to perform sexually being the logical result. DHT plays a key role in this process and is therefore administered in conjunction with such steroids to ease or relieve this annoying side-effect. Proviron is also commonly prescribed by doctors to people with low levels of testosterone, or patients with chronic impotence. Its not perceived as a powerful anabolic, but it gets the job done equally well if not better than other anabolic steroids making it a favorite in medical practices due to its lower chance of abuse.

Mesterolone is generally well liked nonetheless as it delivers very few side-effects in men. In high doses it can cause some virilization symptoms in women. But because of the high level of deactivation and per-destination in the system (albumin, SHBG, 3bHSD, aromatase) quite a lot of it, if not all simply never reaches the androgen receptor where it would cause anabolic effects, but also side-effects. So its relatively safe. Doses between 25 and 250 mg per day are used with no adverse effects. 50 mg per day is usually sufficient to be effective in each of the four cases we mentioned up above, so going higher really isn't necessary. Unlike what some suggest or believe, its not advised that Proviron be used when not used in conjunction with another steroid, as it too is quite suppressive of natural testosterone, leading to all sorts of future complications upon discontinuation. Ranging from loss of libido or erectile dysfunction all the way up to infertility. One would not be aware of such dangers because Proviron fulfills most of the functions of normal levels of testosterone.