Wednesday, December 24, 2014

The effect of Equipoise on the body of the athlete

Steroids (also known as cortisone or corticosteroids) are hormones that occur naturally in the body. Steroids decrease inflammation, suppress the body's immune system, block DNA from being made, as well as block a chemical called histamine (released during an allergic reaction). Steroid medicines are man-made but are similar to these natural hormones. The type of steroids used to treat disease are called corticosteroids. They are different to the anabolic steroids which some athletes and bodybuilders use. Anabolic steroids have very different effects. Steroids are available as tablets, soluble tablets and solutions, creams, ointments, inhalers, and injections.

Oral steroids are steroids that you can take by mouth - tablets, soluble tablets and liquids (solutions). Oral steroids available in the UK include: Betamethasone, Cortisone, Deflazacort, Dexamethasone, Hydrocortisone, Methylprednisolone, Prednisolone and Fludrocortisone acetate. They come in various different brand names. Prednisolone is the most commonly used oral steroid. This leaflet discusses the main possible side-effects of oral steroids as well as other important information if you take oral steroids. Oral steroids are used to treat a large number of conditions. Some examples include: inflammatory bowel diseases (for example, Crohn's disease, ulcerative colitis), autoimmune diseases (for example, autoimmune hepatitis), joint and muscle diseases (for example, rheumatoid arthritis, polymyalgia rheumatica), allergies and asthma. They are also used to treat some cancers. In addition they can be prescribed as replacement treatment for people who have stopped making their own steroids - Addison's disease.

Consider the effect of Equipoise:
Equipoise was actually created while attempting to make a product which would be be a long acting injectable Dianabol (Methandrostenolone). What was actually created was a product which, in the real world acts nothing like D-bol, despite its similarity to it chemically. A simple way to think of Equipoise, chemically at least, is simply as Dianabol without the 17-alpha-methyl group (thats the thing which makes D-bol able to be ingested orally and not be destroyed by your liver). To make Equipoise, a double bond was added between carbon atoms 1 and 2 of the Steran Nucleus of Testosterone. What does this mean? Well, first of all, since Equipoise was created by one simple modification in the testosterone molecule, you could rightly suspect that it shares many similarities with it. Equipoise is just as anabolic as testosterone (as you can tell by its anabolic rating above), but only half as androgenic.

Its not very common to compare Equipoise to testosterone, however a far more common comparison is between Equipoise and Deca. Equipoise doesn't actually act much like deca at all. Deca is actually a progestin and a 19-nor derived steroid whereas Equipoise is more closely related to testosterone (being only one double bond differ rent). Duchaine later rescinded his original statement on Equipoise and said that it was disappointing as a mass builder when compared with deca, but a far better drug than for both strength gains and vascularity. Unfortunately, the myth that Equipoise's action is similar to Deca's has persisted for nearly 2 decades after he revised his opinion, this is most evident on internet message boards today, where many will advise against including both of them in a cycle because "they act the same way."

The 1-2 double bond that Equipoise has is responsible for many of its characteristics. First of all, it acts to slow aromatization (conversion into estrogen). The best estimate is that it does so at roughly half the rate of testosterone. This is the best number Ive found in studies. Athletes almost never report estrogenic side effects with Equipoise, even when the dose is up to a gram per week. Virilization (development of male sexual characteristics in women) is almost never seen with this compound, when reasonable doses are used by female athletes. This is one of the few injectable compounds which could be successfully be used by female athletes and bodybuilders, and isn't often faked. That double bond is also responsible for Equipoises resistance for being changed by the 5- 5-Alpha-reductase enzyme. This enzyme converts a small amount of Boldenone into Dihydroboldenone, which is a very potent androgen (7x as anabolic as testosterone). Such a small amount of it is converted that its really of no concern to most athletes taking Equipoise. This factor, plus its low aromatization rate mean athletes don't need to consider using ancillaries with Equipoise.

Equipoise Side Effects:
One of the most pronounced effects in Equipoise is its ability to raise your RBCs (red blood cells). This is very typical of anabolic steroids; however, Equipoise would appear to do it to a slightly greater degree than most. One of the other effects most Equipoise users report is an increased appetite. Its because of this ability to increase appetite that many will include Equipoise in a mass cycle, and its for the quality of muscle gained on it that many will include it in a cutting cycle.

Tuesday, December 16, 2014

Deca Durabolin Effect in bodybuilding

This is an injectable steroid that is a derivative of 19-nortestosterone. It is one of the most popular steroids of all time. Deca is a low androgenic steroid, with high anabolic properties. It is used for developing size and strength. It does not have very high liver toxicity nor does it disturb the body’s own hormone functions too excessively at low doses. Deca Durabolin is a 19-Nor compound (some would say that it is the 19-nor compound), and as such, it shares basically the same characteristics with all of them. One thing unique to Deca, above nearly all steroids, is the mystique it has had for the last quarter of a century. On a personal level, Ive included Deca in cycles at doses ranging from 100mgs/week to 2,000mgs per week. For many, this was and is the final word on Deca. Lets delve into some of the reasons that Deca's mystique may be well deserved. Nandrolone is by far one of the most popular anabolic steroids available. This is due to the compound's affinity for being highly anabolic but relatively mild in terms of androgenic side effects. Nandrolone is the base steroid 19Nor-testosterone, meaning that it is like testosterone in appearance except for the absence of a carbon atom in the 19th position. This small change makes a major difference in the characteristics of the compound. Notably, this change makes Nandrolone a less potent agonist of the androgen receptor. This of course reduces the chance that a user will experience androgenic side effects. Instead of forming Dihydrotestosterone when encountering the 5 alpha reductase enzyme like testosterone does, Nandrolone will form dihydronandrolone. Dihydronandrolone is extremely mild in terms of it's antagonizing the androgen receptor. Therefore androgenic side effects should be far less likely to occur with Nandrolone than with testosterone. It is of note however that Nandrolone is believed to have some activity as a progestin in the body. Although progesterone is a c-19 steroid, removal of this group as in 19-norprogesterone creates a hormone with greater binding affinity for its corresponding receptor. The compound will stimulate the progesterone receptor, along with progesterone. Side effects associated with this activity are similar to some of those related to estrogenic ones including water retention, acne, and gynecomastia among others. However these side effects are fairly rare in comparison to more androgenic compounds.

First of all, Deca Durabolin (and Nandrolone in general) doesn't produce many estrogenic or androgenic side effects. This is because Deca Durabolin has a very low rate of aromatization (conversion to estrogen via the aromatase enzyme), roughly equal to 20% the rate of Testosterone. Deca will aromatize in higher dosages, but not at the rate of testosterone’s or other high androgenic compounds. This drug can be used for cutting or for bulking. Athletes have stacked it with virtually every drug. It is a good base drug on any cycle. Deca is said to have the best effect to side effect ratio of any other steroid.

Women use this drug but only in very low dosages, 25mg per week. Deca has been established as a great soother of sore joints and tendons. Athletes report that sore shoulders, knees, and/or elbows are somehow without pain on the Deca cycle. This may be substantiated by proving it reduces the amount of cortisol getting into muscle tissue during the cycle. Deca also dramatically improves nitrogen retention and recuperation time between workouts. Deca has shown up positive on more steroid tests than any other steroid. This is due to the fact that so many athletes use it, and that it stays in the system at a detectable level for up to a year. The higher the fat content of the user, the longer it stays in your system. Deca can be active from 10-14 days after injection, but weekly injections of 300-600 mgs are common for men. Deca, or more precisely Nandrolone Decanoate, is commonly counterfeited.

Endocrine and Metabolic:
Endocrine side effects noted during exogenous administration of anabolic steroids have included inhibition of endogenous testosterone release by means of feedback inhibition of pituitary luteinizing hormone (LH). Large doses of exogenous anabolic steroids may suppress spermatogenesis through inhibition of pituitary follicle stimulating hormone (FSH). The androgenic activity of anabolic steroids may decrease levels of thyroid-binding globulin and result in decreased total T4 serum levels and increased resin uptake of T3 and T4. Free thyroid hormone levels remain unchanged and there is no clinical evidence of thyroid dysfunction.
Metabolic effects occurring during anabolic steroid therapy in immobilized patients or those with metastatic breast disease have included osteolytic-induced hyperglycemia. Anabolic steroids affect electrolyte balance, nitrogen retention, and urinary calcium excretion. Edema, with and without congestive heart failure, has occurred. Decreased glucose tolerance requiring adjustments in hyperglycemia control has been noted in diabetic patients. Significant increases in low density lipoproteins (LDL) and decreases in high density lipoproteins (HDL) have occurred.

Tuesday, December 9, 2014

Bodybuilders And Anabolic Steroids

Many competitive bodybuilders take anabolic steroids to achieve their freakishly exaggerated physiques. That is no secret. But steroids can be only one part of an extreme regimen that can wreak havoc on the body. Human growth hormone, supplements, painkillers and diuretics can also be used to create the “shrink-wrapped” muscles so prized in the aesthetic. And the high concentration of muscle mass puts stress on the body, as if the lifter were obese. Lifting weights in the gym is “extremely healthy for you,” said Kenneth Wheeler, a former elite bodybuilder known as Flex. “But if you want to be a bodybuilder and compete at the highest level, it has nothing to do with health.” A relatively rare form of kidney disease forced Wheeler to retire in 2003 at age 37, and he needed a kidney transplant later that year. Determining the extent of the damage that bodybuilders inflict on themselves is difficult, in part because there is little interest in financing studies on such an extreme group, and because bodybuilders are not always honest about what they take. That is why a case study published last month by a top kidney journal is generating interest in the nephrology and bodybuilding communities. It is among the first to assert a direct link between long-term steroid use and kidney disease. The study began 10 years ago when a kidney pathologist at Columbia University Medical Center in New York noticed that a bodybuilder had an advanced form of kidney disease. Curious, she started looking for similar cases and eventually studied 10 men with serious kidney damage who acknowledged using steroids. Nine were bodybuilders and one was a competitive power lifter with a similar training routine.

All 10 men in the case series, published in November by the Journal of the American Society of Nephrology, showed damage to the filters of the kidney. Nine had an irreversible disease known as focal segmental glomerulosclerosis — the same disease contracted by Wheeler — even though the men in the study did not have other apparent risk factors. Their disease was worse than in obese patients with a higher body-mass index, suggesting that steroids — combined with the other practices — might be harming the kidneys.  Bodybuilders and modern fitness models present physiques that make them look like aliens from outer space compared to the average person with a beer belly you meet on the street. They look quite powerful, strong, aesthetic and lean. Since the time of Arnold Schwarzenegger and before bodybuilding has been considered always a source of health and longevity. Many even consider it the fountain of youth. Unfortunately, behind the scenes the story is quite different and it seems that inside that muscular and lean body there’s often damaged hardware that can cause bugs in the future. There’s nothing wrong with exercising. Since the beginning of time exercising has been presented as a healthy activity that makes you a better version of yourself. What doesn’t kill you, makes you stronger, correct? This is one of the reasons why many people often refer to gyms as health clubs. They lift multiple plates on each side of the barbell and don’t fuck around with nonsense. Similar ego lifting is known to cause multiple injuries and it’s not uncommon for a bodybuilder to tear a few tendons during his career.

People like Branch Warren have become notorious for their poor training form. The idea behind Branch Warren’s style of lifting is simple: if the bar ain’t bending, you are just pretending.  If you put your ego to the side just for a little bit, you can avoid a lot of potential injuries. While exercising can obviously cause health problems it’s not what makes bodybuilding and fitness unhealthy. It’s actually the cause of the least amount of problems bodybuilders and fitness models experience. There is no doubt that steroids and other performance-enhancing drugs (PED) have been part of bodybuilding since the very beginning of the sport and they are the reason why bodybuilders keep getting bigger and bigger. It’s not that nutrition and training changes – it’s the syringe size and its content that increase and improve. Anabolic steroids are a huge part of a bodybuilder’s life. Most bodybuilders would rather have a coach experienced with drug protocols than somebody who knows how to train and eat correctly. This is not a surprise since no matter how well your training is, you will never reach the physical development of modern professionals unless you ‘juice’. If you don’t have somebody to tell you how to win the chemical war, you are doomed to fail in your pursuit of a super muscular body. In general, steroids are not as dangerous as people make them appear. They are medical products that in certain situations save people’s lives and help them get back on their feet. That’s one of the main reason why anabolic steroids are produced in the the first place. They are like morphine – it can help you or break you. The main reason why bodybuilders as well as modern fitness models experience health problems due to steroid abuse is the amount of different drugs they use. It’s not uncommon for a bodybuilder to be on a few grams of testosterone a week coupled with a large cocktail of other powerful muscle enlarging pills. Abuse of similar substances is known to cause liver, kidney and heart failure. There are also many minor side effects such as hair loss, testicular atrophy and reduction of natural testosterone production. Females are also seriously affected by anabolic steroids and after a certain point they start turning into men.

Tuesday, December 2, 2014

Deca Durabolin - Nandrolone Oil-Based Injection

In general, USA Deca Durabolin is probably the post popular, sought-after steroid. It is oil-based and comes in either 100-mg./ml or 200-mg/ml. injection. The drug is considered slow to convert to estrogen, a good mass and strength-builder and, for a variety of suggested chemical reasons (none really proven), it is considered to ease joint pain. However, it will suppress the pituitary-testosterone loop in due time. The USA pharmaceutical versions are hard to obtain. Lately, Some of the Mexican veterinary steroids (of all kinds) have tested poorly.  Deca-Durabolin is the Organon brand name for the injectable steroid Nandrolone Decanoate. This compound came around early in the wave of commercial steroid development, first being made available as a prescription medication in 1962. This steroid is an extremely long acting compound, with the Decanoate ester said to provide this drug a slow release time of up to three or four weeks. While perhaps true in a technical sense, what we find with further investigation is that the release parameters after a single injection are such that a strong release of Nandrolone is really only maintained for one to two weeks. This figure admittedly fails to take into account drug buildup that may occur after multiple injections, which may allow a longer duration of good effect to be seen. Figure 1 is provided to illustrate the release dynamics of a single 200mg injection. As you will see, by the end of the second week levels are already approaching baseline.

World Wide "Deca" is one of the most widely used anabolic steroids. Its popularity is due to the simple fact that it exhibits many very favorable properties. Structurally Nandrolone is very similar to testosterone, although it lacks a carbon atom at the 19t" position (hence its other name 19-nortestosterone). The resulting structure is a steroid that exhibits much weaker androgenic properties than testosterone. Of primary interest is the fact that Nandrolone will not break down to a more potent metabolite in androgen target tissuess. You may remember this is a significant problem with testosterone. Although Nandrolone does undergo reduction via the same (5-alpha reductase) enzyme that produces DHT from testosterone, the result in this case is dihydronandrolone. This metabolite is weaker than the parent Nandrolones, and is far less likely to cause unwanted androgenic side effects. Strong occurrences of oily skin, acne, body/facial hair growth and hair loss occur very rarely. It is however possible for androgenic activity to become apparent with this as any steroid, but with Nandrolone higher than normal doses are usually responsible.

Nandrolone also show an extremely lower tendency for estrogen conversion. For comparison, the rate has been estimated to be only about 20% of that seen with testosterones9. This is because while the liver can convert Nandrolone to estradiol, in other more active sites of steroid aromatization such as adipose tissue nandrolone is far less open to this process. Consequently estrogen related side effects are a much lower concern with this drug. An antiestrogen is likewise rarely needed with Deca, gynecomastia only a worry among sensitive individuals. At the same time water retention is not a usual concern. This effect can occur however, but is most often related to higher dosages. The addition of Proviron and/or Nolvadex should prove sufficient enough to significantly reduce any occurrence. Clearly Deca is a very safe choice among steroids. Actually, many consider it to be the best overall steroid for a man to use when weighing the side effects and results. It should also be noted that in HIV studies, Deca has been shown not only to be effective at safely bringing up the lean body weight of patient, but also to be beneficial to the immune system.

It is of note however that Nandrolone is believed to have some activity as a progestin in the body". Although progesterone is a c-19 steroid, removal of this group as in 19-norprogesterone creates a hormone with greater binding affinity for its corresponding receptor. Sharing this trait, many 19-nor anabolic steroids are shown to have some affinity for the progesterone receptor as well'2. This can lead to some progestin-like activity in the body, and may intensify related side effects. The side effects associated with progesterone are actually quite similar to those of estrogen, including negative feedback inhibition of testosterone production, enhanced rate of fat storage and possibly gynecomastia. Many believe the progestin activity of Deca notably contributes to suppression of testosterone synthesis, which can be marked despite a low tendency for estrogen conversion.

Deca is not known as a very "fast" builder. The muscle building effect of this drug is quite noticeable, but not dramatic. The slow onset and mild properties of this steroid therefore make it more suited for cycles with a longer duration. In general one can expect to gain muscle weight at about half the rate of that with an equal amount of testosterone. A cycle lasting eight to twelve weeks seems to make the most sense, expecting to elicit a slow, even gain of quality mass. Although active in the body for much longer, Deca is usually injected once per week. The dosage for men is usually in the range of 200-600mg. If looking to be specific, it is believed that Deca will exhibit its optimal effect (best gain/side effect ratio) at around 2mg per pound of body weight/weekly. Deca is also a popular steroid among female bodybuilders. They take a much lower dosage on average than men of course, usually around 50mg weekly. Although only slightly androgenic, women are occasionally confronted with virilization symptoms when taking this compound. Should this become a concern, the shorter acting nandrolone Durabolin would be a safer option. This drug stays active for only a few days, greatly reducing the impact of androgenic buildup if withdrawal were indicated.

Wednesday, November 26, 2014

Somatotropic Hormone and bodybuilding

The growth hormones is a polypeptide hormone consisting of 191 amino acids. In humans it is produced in the hypophysis and released if there are the right stimuli (e.g. training, sleep, stress, low blood sugar level). It is now important to understand that the freed HGH (human growth hormones) itself has no direct effect but only stimulates the liver to produce and release insulin-like growth factors and somatomedins. These growth factors are then the ones that cause various effects on the body. The problem, however, is that the liver is only capable of producing a limited amount of these substances so that the effect is limited. If growth hormones are injected they only stimulate the liver to produce and release these substances and thus, as already mentioned, have no direct effect.

The use of these STH somatotropic hormone compounds offers the athlete three performance-enhancing effects. STH (Somatotropic Hormone) has a strong anabolic effect and causes an increased protein synthesis which manifests itself in a muscular hypertrophy (enlargement of muscle cells) and in a muscular hyperplasia (increase of muscle cells.) The latter is very interesting since this increase cannot be obtained by the intake of steroids. This is probably also the reason why STH is called the strongest anabolic hormone. The second effect of STH is its pronounced influence on the burning of fat. It turns more body fat into energy leading to a drastic reduction in fat or allowing the athlete to increase his caloric intake. Third, and often overlooked, is the fact that STH strengthens the connective tissue, tendons, and cartilages which could be one of the main reasons for the significant increase in strength experienced by many athletes. Several bodybuilders and powerlifters report that through the simultaneous intake with steroids STH protects the athlete from injuries while increasing his strength.

There are three hormones which are needed at the same time in order to allow for maximum anabolic effect. These are STH, insulin, and an LT-3 thyroid hormone, such as, for example, Cytomel. Only then can the liver produce and release an optimal amount of somatomedin and insulin-like growth factors. This anabolic effect can be further enhanced by taking a substance with an anticatabolic effect. These substances are-everybody should probably know by now-anabolic/androgenic steroids or Clenbuterol. Then a synergetic effect takes place.'Are you still wondering why pro bodybuilders are so incredibly massive but, at the same time, totally ripped while you are not. Most athletes have tried STH during preparation for a competition in that phase when the diet is calorie-reduced.  The body usually reacts by reducing the release of insulin and of the L-T3 thyroid hormone.  Those who combine Clenbuterol with STH, should know that Clenbuterol (like Ephedrine) reduces the body's own release of insulin and L-T3. True, this seems a little complicated and when reading it for the first time it might be a little confusing; however it really is true: STH has a significant influence on several hormones in the human body; this does not allow for a simple administration schedule. Since most athletes vho want to use STH can only obtain it if prescribed by a physician, the only supply source remains the black market. And this is certainly another reason why some athletes might not have been very happy with the effect of the purchased compound. In addition to a display of labels in the Dutch or Russian language the fakes are distinguished from the original product, in sofar as the dry substance is not present as lyophilic but present as loose powder. Nowhere can this much money be made except by faking STH. Who has ever held original growth hormones in his hand and known how they should look?. In a few very rare cases the body reacts by developing antibodies to the exogenous STH, thus making it ineffective. The question of the right dosage, as well as the type and duration of application, is very difficult to answer. Since there is no scientific research showing how STH should be taken for performance improvement, we can only rely on empirical data, that is experimental values. The respective manufacturers indicate that in cases of hypophysially stunted growth due to lacking or insuffieient release of growt hormones by the hypophysis, a weekly average dose of 0.3 I.U/ week per pound of body weight should be taken. An athlete weighting 200 pounds, therefore, would have to inject 60 I.U. weekly. The dosage would be divided into three intramuscular injections of 20 I.U. each. Subcutaneous injections (under the skin) are another form of intake which, however would have to be injected daily, usually 8 I.U. per day. Top athletes usually inject 4-16 I.U./day. Ordinarily, daily subcutaneous injections are preferred. Since STH has a half life time of less than one hour, it is not surprising that some athletes divide their dail dose into three or four subcutaneous injections of 2-4 I.U. each. Application of regular small dosages seems to bring the most effective results. This also has its reasons: When STH is injected, serum concentration in the blood rises quickly, meaning that the effect is almost immediate. As we know, STH stimulates the liver to produce and release somatomedins and insulin like growth factors which in turn effect the desired results in the body. Since the liver can only produce a limited amount of these substances, we doubt that larger STH injections will induce the liver to produce instantaneously a larger quantity of somatomedins and insulin-like growth factors. It seems more likely that the liver will react more favorably to smaller dosages. If the STH solution is injected subcutaneously several consecutive times at the same point of injection, a loss of fat tissue is possible. Therefore, the point of injection, or even better, the entire sisde of the body should be continuously, changed in order to avoid a loss of local fat tissue (lipoathrophy) in the injection cell. One thing has manifested itself over the years: The effect of STH is dosage-dependent. This means either invest a lot of money and do it right or do not even begin. Half-hearted attempts are condemned to failure Minimum effective dosages seem to start at 4 I.U. per day. For comparison: the hypophysis of a healthy, adult, releases 0.5-1.5 I.U. growth hormones daily.

Our experience is that STH is taken over a prolonged period, from at least six weeks to several months. It is interesting to note that the effect of STH does not stop after a few weeks; this usually allows for continued improvements at a steady dosage. Bodybuilders who have had positive results with STH have reported that the build-up strength and, in particular, the newly-gained muscle system were essentially maintained after discontinuance of the product. It remains to be clarified what happens with the insulin and LT-3 thyroid hormone. Athletes who take STH in their build-up phase usually do not need exogenous insulin. It is recommended, in this case, that the athlete eats a complete meal every three hours, resulting in 6-7 meals day. This causes the body to continuously release insulin so that the blood sugar level does not fall too low. The use of LT-3 thyroid hormones, in this phase, is carried out reluctantly by athletes. In any case, you must have a physician check the thyroid hormone level during the intake of STH. Simultaneous use of anabolic /androgenic steroids and/or Clenbuterol is usually appropriate. During the preparation for a competition the use of thyroid hormones steadily increases.

Tuesday, November 18, 2014

The Benefits of Halotestin

It is one of the most powerful anabolic steroids of all time and one of the fastest acting to boot yet you will not find it to be commonly used by the majority of performance enhancing athletes; in the gym rat circles it can actually be somewhat of a rarity. While this remains true there are few steroids that equal the raw power of Fluoxymesterone commonly known as Halotestin and often simply referred to as Halo. Far more anabolic and androgenic than testosterone, the hormone by-which all anabolic steroids are measured, it is unique in its anabolic and androgenic nature. Halotestin by its very nature is both highly anabolic and highly androgenic yet it displays almost no androgenic effects leaving nothing but an anabolic end. As Halo is purely anabolic in action it is one of the absolute best strength increasing steroids on the market but in-terms of mass it will do very little; in-fact, we can safely say for mass it really won’t do anything at all. In the world of competitive bodybuilding, especially at the elite levels Halotestin is often viewed as a staple in last minute preparation and in this case it really doesn’t have anything to do with strength. Halo has the ability to greatly harden a physique, a lean physique, that is correct, one must already be very lean to reap this benefit; Halo will not magically take a physique that has a layer of fat and make it hard. To reap this reward one must be very lean, preferably already below 6% but even lower is better. Of equal importance is the “push” Halotestin can provide in the final weeks of dieting, competitive bodybuilding diets are some of the hardest and most brutal diets man has ever come up with and towards the end when body fat is low and energy levels are drained pushing through the final training sessions can be the hardest thing anyone ever undertakes. However, with Halotestin use we have one of the few anabolic steroids that actually and truly increases aggression allowing the competitor to push through his final training, giving him the edge he needs that could not be obtained on a calorie restricted diet such as this without Halo. When examining the side-effects of Halotestin we will find they are very similar to some of the more popular DHT based anabolic steroids, side-effects such as acne and hair-loss can be a concern but there are two things we must remember and consider. All steroids and all medications, steroidal and non-steroidal alike carry with them the possibility of negative side-effects but possibility in no way means guaranteed, it simply means the potential is there and the level of potential will vary greatly from one person to the next. Further, because we will only supplement with Halotestin for very short periods of time the possible DHT type side-effects are of very little concern. 4 weeks of total Halo use is fairly common but even use for as little as 2 weeks is not as uncommon as you might think. For the individual who goes past the 4 week mark this is where side-effects may begin to become problematic, most notably revolving around the liver; if you recall Halo greatly increases liver enzyme values. Liver damage is without question the most serious concern when Halo is used and for that reason use must necessarily remain responsible if we are to combat this issue and keep our liver healthy.

It should come as no surprise, Halotestin is most commonly found among strength athletes, particularly power lifters, however, it also has a very popular use among competitive bodybuilders, particularly during the latter portion of contest prep dieting. As these are the two most common groups who use the steroid it is rarely found among the majority of steroid users and this is the gym rat group, individuals who do not play or participate in any competitive sport, they are not bodybuilders competitively, they do not power lift competitively, they simply train for trainings sake in order to look and feel better. The reason is simple; while Halotestin is very powerful it is also very harsh and for the gym rat there are many other choices far safer and efficient to meet their desired goals. Derived from testosterone, many of the effects and traits can be akin to popular Dihydrotestosterone (DHT) steroids, although to a greater degree. As a testosterone derivative one might expect this steroid to aromatize heavily and while this would make sense it is however not the case, as Halo does not aromatize at all. What truly makes Halo special is in its ability to dramatically increase hemoglobin levels and the mass and structure of red blood cells by way of action in-which it correlates with erythropoietin. It is by this trait Halotestin gives us such a rapid and massive increase in strength and while other anabolic steroids can perform in a similar action Halo simply does it to a much larger degree. Like many other steroids Halotestin also appears to have a positive impact on metabolic function and even direct oxidation of fatty acids; however, this affect is so slight that it’s almost not worth mentioning, again making strength the primary attribute.

As are most oral anabolic steroids Halotestin belongs to the 17 Alpha-Alkylated class (17-aa.) This classification refers to an alteration in the hormones structure, in this case Fluoxymesterone and refers to the hormones structure being altered at the 17th carbon position in order to allow survival in the body; without this alteration the hormone would be destroyed by the liver and it would never make it to the blood where activity becomes present. While this structural change allows the hormone to perform its desired action it is not without fault, for as you may understand 17-aa anabolic steroids are liver toxic and Halotestin makes no exception. In the case of Halo there is however a slight difference in toxicity levels when compared to many other oral 17-aa steroids and that is it possesses one of the highest levels of toxicity of all. The use of Halotestin can and will more than likely dramatically increase liver enzyme values and it is for this reason the steroid should only be used for short periods of time and in responsible doses. For those who use responsibly, while liver enzyme levels will increase they will return to normal shortly after use is discontinued, assuming you have a healthy liver to begin with. It is very common for the benefits of Halotestin to be compared to Winstrol (Stanozolol) and in some ways this isn’t inaccurate as both will and are designed for increasing strength and both steroids can lead to a harder physique, however, the difference in potency is not even close. Halo will increase strength at a rate incomparable to Winstrol and most anabolic steroids and in such rapid fashion that we can in many ways consider it the king of strength. Even so, while strength increasing is its primary function, due to the high liver toxicity most athletes will not use it for more than 4 weeks at a time and generally to reap the greatest benefit the final 4 weeks before the desired competition is at hand. As we eluded to there is another benefit to Halo beyond strength, in-fact there are two but strength is and will always remain its primary purpose. As it pertains to Halotestin we actually have one of the few anabolic steroids that can really provide an aggressive bump that will allow the individual to perform at a higher level of intensity. As you can imagine this is perfect for the power lifter and can greatly aid the bodybuilder in his contest diet. It is one of those things that is necessary and it should not be feared, after all, aggression is praised in most aspects of competitive sports, you want aggressive football players who attack on the field, you want aggressive baseball players who swing for the fence, the list goes on and on. There is an old saying regarding rage and anabolic steroids and as Halo can truly increase aggression it is perhaps here that it fits best. If you’re a jerk before you use steroids you’ll simply be a more aggressive jerk with steroids, if you’re a sane individual and not a jackass, you’ll still be the same sane jackass free individual when steroid use is at hand, you will simply now have more aggression to put towards your athletic performance whatever that might be.

Tuesday, November 11, 2014

Benefits of oral steroid Proviron

Proviron (or Mesterolone) is an oral Dihydrotestosterone-steroid compound similar to Masteron. It is admired for its ability to balance a deficiency of androgen formation that tends to fall gradually with increasing age. This anabolic androgenic steroid is medically prescribed for treatment of all conditions caused by deficient endogenous androgen formation. The IUPAC name of Proviron is 1 alpha-methyl-17 beta-hydroxy-5 alpha-androstan-3-one and the molecular mass of this prescription drug is 304.467 g/mol at the base. It has the molecular formula of C20H32O2 and has an active life of eight to twelve hours though its effects can be experienced up to 24 hours. The drug has an anabolic-androgenic ratio of 100-150: 30-40 and can be detected over a period of 5-6 weeks.

Mesterolone is commonly used to maintain libido off-cycle and also relatively and temporarily improving vascularity. This steroid is even used to treat male patients struggling with impotency or lack of testosterone, low libido, and erectile malfunction. It also has the ability to promote improved release of luteinizing hormone and follicle-stimulating hormone for stimulating testes so that more testosterone can be produced. This steroid is well tolerated by the liver and does not impair spermatogenesis. Proviron is recommended for treating declining physical activity and mental alertness in middle- and old-aged men. This anabolic androgenic steroid has the ability to greatly promote direct lipolysis and even promote more of free testosterone by its sex hormone binding globulin (SHBG)-binding nature. It also binds strongly the androgen receptors and SHBG. This steroid can even work to increase the activity of other steroids in an anabolic steroid cycle by displacing a higher percentage of SHBG into a free and unbound state due to its extremely high affinity for plasma binding proteins such as SHBG. Use of this drug is also useful to reduce estrogenic side effects of other steroids like water-retention, lowered sex drive, gynecomastia, etc. as Proviron prevents the formation of estrogen in the first place.

In addition to this, this steroid can also be used for treating reduced efficiency, lack of concentration, weak memory, disturbances of libido and potency, irritability, and disturbances of sleep. It is also recommended for treating depressive moods, and general vegetative complaints that are often attributed to androgen-deficiency. This anabolic steroid may also be recommended in cases of diminished potency where androgen-deficiency is not the primary cause.

Proviron can lead to a dramatic increase in the hardness and density of the muscles. It is favored by bodybuilders and power lifters during contest preparations when a lower estrogen/high androgen level is particularly sought after. Proviron also has the ability to promote the development of secondary male sex characteristics in cases of prepuberal hypogonadism and stimulate growth, development, and function of androgen-dependent target organs.

It may even be recommended for treating patients diagnosed with infertility and can be used as a substitution therapy in cases where a loss of gonadal function has occurred post-pubertal. The chances of procreation can be increased with the use of this steroid as Proviron can increase sperm count and quality. The recommended dose of Proviron for men is 25 mg three times daily. This steroid can be used for a long period of time as it is not a 17a-alkylated compound. Some athletes may use Proviron may use it in daily doses of 25-100mg per day (for men) and 40-60mg per day (for women).

Tuesday, November 4, 2014

Trenbolone For Athletes And Bodybuilders

The chemical name of Trenbolone is 17β-Hydroxyestra-4, 9, 11-trien-3-one and it has a half life of nearly 2-3 days. The molecular weight of Trenbolone is 270.37 g/mol at the base and its molecular formula is C18H22O2. The 19-nor steroid that is derived from the compound Nandrolone has the anabolic-androgenic ratio of 500:500, which means it is five times as potent as Testosterone. This steroid is generally administered as ester derivatives like Trenbolone acetate, Trenbolone enanthate and Trenbolone cyclohexylmethylcarbonate (Parabolan). It is important to note that the difference between Trenbolone acetate and Trenbolone enanthate lies in the count of attached esters. The enanthate version of this steroid has seven attached esters, while the acetate version of Trenbolone has two esters. In addition to this, Trenbolone acetate’s esters are more potent than that of Trenbolone enanthate, when compared milligram to milligram. Classified as a Schedule III drug, this anabolic androgenic steroid is rated by sport coaches and gym instructors as the best alternative to Primobolan. Trenbolone use is associated with suppression of excess estrogens, reduction in levels of catabolism and stimulation of appetite.

One of the best things about Trenbolone is that it allows athletes and others to reap the optimum advantages of ingested vitamins and minerals. Trenbolone is also an effective steroid to promote efficient use and processing of food. This short-acting steroid is equally beneficial to stimulation new tissue formation that in turn promotes muscle mass and body strength. Trenbolone use is not linked to the development of feminine sexual characteristics in men, unlike some testosterone-based steroids. In addition to these advantages, Trenbolone also has the ability to enhance muscle tissue properties by inhibiting protein mobilization and breakdown of muscles in gluconeogenesis. Moreover, Trenbolone can even promote improvements in the context of Insulin-like growth factor-1 and satellite cells that play a critical role in repairing damaged muscle tissue. This steroid also demonstrates efficacy in reducing body fat as it has a strong cortisol-reducing effect along with the ability to bind to the glucocorticoid receptor. Used for both anabolic bulking and cutting cycles, this anabolic steroid is directly associated with muscle mass, endurance, aggression, lean muscle mass, and endurance gains. Trenbolone rarely leads to aromatization, which makes it an excellent choice for athletes (using steroids) prone to estrogenic side effects like acne, oily skin, and gynecomastia. Considered by many as a body-transforming drug, Trenbolone is also useful for balanced growth and development of secondary male sexual characteristics.

Recommended Dose Of Trenbolone:
Male athletes usually administer Trenbolone in daily dosages of 50-100mg and stack it with Anadrol, Dianabol, or Testosterone compounds such as Testosterone Propionate or Testosterone Cypionate. Athletes using this steroid are advised to run Letrozole to control progesterone levels and Bromocriptine, Vitamin B6, or Cabergoline for keeping a check on the levels of prolactin. Trenbolone acetate is ideally used by male athletes in daily dosages of 50-100mg while the ideal dose of Trenbolone enanthate is 300-600mg every week for men.

renbolone is not recommended to girls and women, who may get pregnant, while using it or those who are already pregnant or breastfeeding. Use of this steroid is also not recommended to those allergic to the ingredients of Trenbolone or people who are diagnosed with health complications like liver/kidney damage, prostate cancer, breast cancer, testicular cancer, high blood pressure, or stroke. Trenbolone should only be used for legal (medicinal) purposes and after a qualified medical practitioner has recommended use of this steroid following thorough review of medical reports and history. This steroid should not be overdosed in hopes of quick results and medical assistance should be sought immediately after discontinuing use of Trenbolone in case any abnormality is experienced by athletes using this steroid.

Trenbolone Abuse And Side Effects:
Trenbolone use for extended periods of time can result in side effects like breast growth and lactation in men, anxiety, increased aggression, increased libido, elevated blood pressure, insomnia, and night sweats. Trenbolone abuse or overdosing may lead to liver and kidney failure or clitoris enlargement, male pattern baldness, oily skin, acne, prostate enlargement or water retention.

Tuesday, October 28, 2014

Testosterone Replacement Therapy

Testosterone Replacement Therapy these words have become more common with every passing year but many still have no clue as to what testosterone replacement therapy really is. You’ve seen the commercials for “Low-T” and if you ask most men they sound great but many still have no clue “Low-T” is nothing more than testosterone replacement therapy and this therapy unknown to even more is nothing more than a legal prescription for anabolic steroids. That’s right, anabolic steroids, testosterone replacement therapy refers to a treatment in-which low levels of the naturally occurring hormone testosterone are brought back into an adequate range. To perform this function the anabolic steroid testosterone, a synthetic version of the hormone our body produces must be administered.

If you possess any understanding of the performance enhancing world, on it's surface the idea of testosterone replacement therapy may bring you a sigh of relief but more than likely it probably irritates you at the same time. After all, for years we’ve been told anabolic steroids are brewed in the bowels of hell but if you receive testosterone replacement therapy this same hormone from which all anabolic steroids are derived from, now it’s a welcomed beacon of hope.

Let’s from this point on be clear and precise, these advertisements for “Low-T” treatment and things of this nature are nothing more than advertisements and promotions for anabolic steroids. When you inquire about testosterone replacement therapy understand you’re inquiring regarding anabolic steroids; let’s call a spade a spade. We are still a long way off from anabolic steroids being generally accepted by the whole of society but it is within testosterone replacement therapy this acceptance holds its most promising form.

Testosterone Injection for HRT:
For the individual who has been prescribed hormone replacement therapy (HRT) if he receives a regular testosterone injection as part of this treatment, generally 250mg will be the max dose given, although a dose of 100mg-200mg every 7-14 days is a far more common testosterone injection for the HRT patient. In the U.S. users will generally be prescribed Testosterone Cypionate or Testosterone Propionate and the total injection dose will be based on the milligrams provided by the particular testosterone being used taking into account the half-life and then determining total dosing levels to meet this person’s needs. For example, if an individual is prescribed a dose of 200mg every two weeks one testosterone injection of Cypionate every two weeks is all that is needed. If the individual is prescribed Testosterone Propionate at the same dosing level, 200mg every two weeks, he would need to inject approximately 50mg every 3-4 days. You and your physician will determine what is best for you. Although one bi-weekly injection is far more appealing some individuals will be able to maintain a more stable level with frequent doses of testosterone at a lower level making more frequent injections needed. For the performance enhancer a testosterone injection will need to far surpass HRT levels if we are to reach performance enhancing levels. The idea behind HRT is to simply increase testosterone levels in a manner that returns them to normal. For the performance enhancer the idea is to go beyond normal, to give our body an amount of testosterone it is incapable of producing beyond natural levels. This type of testosterone dosing is commonly referred to as a Supra physiological dose and for most this will fall in the 400mg-500mg per week range at a minimum. Much less and you won’t see any true gains or benefit.

Thursday, October 23, 2014

Sildenafil or "vitamin V" and bodybuilding

Viagra can be used to try and solve the many erectile problems which are caused by diabetes. It is only safe to use this method of treatment as long as your diabetes is properly monitored and under control and it is extremely important that you make sure that you have had help and guidance from your GP about your condition and the best way to treat its side effects. A recent study which looked at the success rate of Viagra in diabetic men found that there was an increase of ‘successful intercourse attempts’ by 26.7%.  The main symptom of erectile dysfunction is that you are unable to have an erection at any time or under any circumstance. The other main symptom is when your erection is not able to last throughout sexual activity. If these symptoms only happen once or twice then there is normally nothing to worry about, as the vast majority of men have experienced erectile dysfunctions within their life time. It is when these problems become persistent and are ruling your day to day life that you should seek medical advice.
There are some simple questions that you can ask yourself to see whether you should seek help about your erection problems. You need to ask is your sex life being affected by these problems and has intercourse become infrequent due to your condition. You then need to think about why sexual intercourse has become infrequent is this because of vaginal penetration becoming impossible or are you constantly suffering from premature ejaculations.

Another useful question to ask yourself is how firm your erections are and how do they alter under different circumstances. You should ask yourself questions like does your erectile dysfunction happen when you are with a particular partner, because if so this could be a psychological problem. This particular erective problem could be down to relationship problems or low libido which would be treated with therapy or counseling rather than a medical issue that needs treatment with medicines or surgery. 

Sildenafil is categorized as a vasodilator and originally was meant to be an aid for high blood pressure. However, it proved to be effective for erectile dysfunction, and it is currently marketed for this purpose. It works by relaxing blood vessels in the penis, which improves blood flow. This property makes it attractive to bodybuilders as well. Bodybuilders take Sildenafil or "vitamin V" as it is often called, along with anabolic steroids prior to a workout. The theory is that the drug's ability to dilate a person's blood vessels will help deliver these steroids to muscles, according to a June 2008 "New York Daily News" article. Bodybuilders who use amino acids, legal supplements and vitamins may operate under the same theory regarding sildenafil. This drug also counteracts the impotence that is sometimes caused by testosterone injections meant to increase muscle mass.

The most famous drug in the world is sildenafil citrate. What’s that? You never heard of it? Perhaps you’re more familiar with its trade name, Viagra. Viagra was once known only as UK-92, 480. The UK portion of the name referred to the United Kingdom, where Viagra was developed in the labs of the giant drug company Pfizer. Chemists were attempting to produce a drug that could effectively treat high blood pressure and angina pectoris, which is pain in the chest related to coronary artery disease. Although the new compound proved weak in treating angina, it produced a readily apparent side effect: pronounced penile erection. The suits at Pfizer immediately recognized the broad implications of the discovery and patented the drug in 1996. The trade name Viagra was chosen, and the FDA approved the drug in 1998. The era of the little blue pill had begun. Viagra works by preventing the premature breakdown of cyclic GMP, a substance that operates at the cellular level to relax smooth muscle. When that happens in the tissues of the penis, blood flow is increased, resulting in penile erection. Viagra increases the presence of cyclic GMP by inhibiting phosphodiesterase type-5, an enzyme that helps break it down. One of the more interesting uses of Viagra has been in sports. Famed baseball pitcher Roger Clemens denied using performance-enhancing drugs during his baseball career but openly admitted using Viagra—not for sexual purposes but rather because he was told that it could enhance endurance and increase oxygen delivery to muscles. Clemens said that it produced facial flushing and a rapidly beating heart. An Italian professional cyclist was suspended after being caught with 82 unprescribed Viagra pills. Victor Conte, architect of the infamous BALCO drug scandal, said that he routinely provided Viagra to such famous athletes as Barry Bonds and Marion Jones. While many of Viagra’s properties seem impressive and despite its apparent widespread availability over the Internet, it’s nonetheless important to remember that it’s a potent drug. The most common adverse effects associated with Viagra include headaches, flushing, indigestion, nasal congestion—a nose-on?—and impaired vision. Some users find themselves seeing everything with a blue tint. Getting too enthusiastic or using too large a dose can cause an erection that doesn’t subside, a condition known as priapism. That can cause serious injury to the penis. Even worse, Viagra can induce severe low blood pressure, even a heart attack in rare instances. A more recent side effect linked to the drug is sudden hearing loss.

Thursday, October 16, 2014

What is Andropause?

Andropause is in many ways simply male-menopause and often referred to as “manopause.” In short, the condition can be explained very easily as it exists simply on the basis of declining androgen production within the body, most notably testosterone and dehydroepiandrosterone and to a degree the increase in Sex Hormone-Binding Globulin (SHBG); direct androgen production is however the primary concern. While menopause and Andropause share some strong similarities there is one very distinctive difference that must be noted. When a woman goes through menopause the onset of the condition is almost instant, the drop or decline in adequate hormonal production is very quick and can become quite bothersome almost overnight. Andropause is however in most cases a little different. Andropause is something that will typically not manifest itself in such a quick and dramatic fashion but rather hormonal decline is slow and steady over a period of many years. How fast the decline will vary from one man to the next and often quite significantly but generally speeding up each and every year as the man ages.

While several varying androgens can be affected testosterone is generally the most important one and the one that will have the greatest negative effect when in decline. You’ve probably already seen the commercials on T.V. talking about low testosterone often referring to it as “Low-T” and in medical practice such a condition is most commonly referred to as hypogonadism. Generally speaking, hypogonadism and Andropause refer to the same thing with Andropause encompassing the total androgen production as a whole, with hypogonadism generally referring only to the androgen testosterone. In any case there are six androgens worthy of note, Androstenediol, Androstenedione (Andro), Androsterone, Dehydroepiandrosterone (DHEA), Dihydrotestosterone (DHT) and Testosterone; testosterone being the primary for which all exist and the only one of high particular importance. 

The effects of Andropause while generally not life-threatening can be beyond bothersome and can in-fact be gateway that opens the door to more serious conditions later down the line that are indeed life-threatening. In short, men who suffer from Andropause will notice their quality of life in a constant state of decline and as this decline is brought about slowly by the time it has really become a problem many men have become accustomed to it. Often such conditions are simply attributed to age and as hormonal decline is a part of age, on its surface this assumption is not without some level of truth. However, if age were the only factor all men would experience Andropause to a similar degree but this is not the case; many men never experience the symptoms to a large degree and in that light things such as genetics or predisposition and lifestyle choices necessarily come into play.

How great of an effect can Andropause have on your quality of life? The condition has the potential to affect sexual function, your appearance, your physical and mental well-being to a far reaching degree with the most common symptoms including:

    Decline or Total Loss of Libido
    Erectile Dysfunction
    Loss of Strength
    Loss of Muscle Tissue & Mass
    Increased Body-Fat
    Lack of Energy
    Lack of Focus
    Weakened Immune System

Your testosterone levels are going to decline as you age, in this there is no escape and as it declines, in many cases other androgen's will follow. However, the lifestyle choices you make can play a factor and you can make adjustments to your life to aid in staving off the condition but understand when Andropause is a reality there is generally no turning back; you will require therapy and you will require it for the remainder of your life. As low testosterone is the primary concern the individual will necessarily do all he can to aid in maintaining proper levels and by and large it is our physical condition and stress levels that dictate this to the greatest degree. Maintaining a healthy body weight or more specifically a healthy body-fat to muscle mass ratio will be your primary tool in staving off Andropause. Your physical condition is of the utmost importance and as a healthy diet rich in healthy fats, especially of the Omega-Fatty Acid nature as well as regular physical activity have all be linked to promoting testosterone production, these are factors that must be considered.

Further, stress as eluded to can play a big role and it can come in many forms. The presence of stress in our life often brings with it the presence of glucocorticoid steroids in abundance and such hormones destroy muscle tissue and promote body-fat as well as leave us generally sluggish. Such stress can be caused by our simple daily lives through work and home, this is true but factors such as lack of rest, improper diet that does not promote adequate physical recovery, over training in the gym or in any activity can all lead to an abundant release of these muscle destroying and fat promoting hormones and ultimately lead to Andropause. When Andropause is determined you will find there is only one true treatment but because such a treatment is built around a very emotional topic many doctors will avoid it until all other options have been tried. Let’s be clear, if you suffer from Andropause there is only one solution, at this stage in the game while improving your lifestyle choices will aid you in the long run they will not provide a solid solution, rather they should be in addition to the therapy you need. To treat Andropause you will need to be placed on a Hormone Replacement Therapy (HRT) plan, then and only then will you see your condition improved and this improvement will work almost every single time. It is true, there is no permanent cure for Andropause for example, once an individual suffers from low testosterone he will always need Testosterone Replacement Therapy (TRT) generally with one exception. Some performance enhancing athletes fall prey to low testosterone at a young age; once steroid use has been discontinued and laid aside they no longer have the ability to naturally produce the hormones they need; generally this is due to abuse of the hormones; many athletes who use responsibly never have a problem. In such cases an HRT plan that generally includes testosterone, in-fact a simple TRT plan may be all that is needed can lead to eliminating the problem. At the same time it may not and this individual may too find himself on HRT for the remainder of his life.

Tuesday, September 23, 2014

Steroid cycles for novice

People who wish to cut fat and add muscles simultaneously and want to utilize legal and relieve drugs must confer with a dr. before using any anabolic steroid. The clip period in which a individual utilizes anabolic steroids is named anabolic steroid cycle. The steroid rounds can include also taking an anabolic steroid at the beginning of the cycle and finish with another steroid, to raise the wanted consequence.

Steroids, as synthetic versions of the testosterone, are stimulating the muscles development. Users will look strong and big on the outside, forgetting the side upshots, that may be creating failing inside.

Steroid stacks have turn uped to be the most efficient style to construct musculus than when the athlete utilizes one type. The utilize of more than one steroid in an anabolic steroid cycle is dramatically increasing the peril of side upshots. This is the ground why the steroids users will stack non-anabolic drugs to minimize the harmful steroid side upshots.

An anabolic steroid cycle is the period where a users uptakes this type of drugs. A long anabolic steroid cycle will really touch the hypothalamus / pituitary gland / testicular axis to bump. HPT suppression will do necessary a permanent testosterone therapy. Many steroid abusers are stacking drugs, cycling or pyramiding is defining the practice of gradually increasing and gradually decreasing anabolic steroid doses over a period if clip.

Steroid cycle continuance depend on the drug users. Some mortals are often against short rounds and long periods of time off; some are suggesting a old ages one shot utilize to have optimal issues. In reality, it is really up to the individual to take the cycle that lawsuits best for him. Tiroes must watch the consumption continuance because the anabolic steroids are strong. Easily aromatized steroids should be employed for only short intervals, less than eight weeks. After this period, it is necessary a interruption of at least as long as the previous period. The physical structure requires clip to bump and remainder.

The users who are not respecting these indicants must check up on often their wellness status. The fact that anabolic steroids are not acting dramatically is making some users to found the anabolic steroid cycle for a long clip period. The best solution is to construct the muscles tissues using traditional methods, such as preparation and appropriate diet.

Many athletes do not understand these prescriptions and bump a cycle of three or four months most appropriate. The athlete must avoid the utilize of steroids an old ages after a steroid cycle, in order to prize the natural hormonal balance. The physical structure really requires a clip to retrieve the natural hormonal balance. Someone must insure that there are only very little possibilities of future side upshots. If an individual believes that these upshots are reversible, they are wrong. Problems with libido, virility, sterility can look because the physical structure was overloaded with male internal secretions for years. Anabolic steroid rounds are involving high blood pressure level, liver toxicity, high cholesterol grades and athlete must throttle the continuance on anabolic steroid rounds if they are not avoiding it completely.

Friday, September 19, 2014

Peptides how they work and why would a player use them?

Peptides are a small chain of amino acids that isn’t quite long enough to be considered a full protein (less than 50 units). They are, in essence, the building blocks that create protein.

In a supplement form peptides come in different chemical compounds. The ones the ACC report identifies as being used within the Australian sporting community are known as GHRP-2, GHRP-6 and CJC-1295. IGF, MGF and SARMs are identified by the ACC as commonly used peptides used in the bodybuilding community. The next big question to consider is why an athlete would consider using peptides.

Peptides are used for their anabolic effect on an athlete’s muscle mass. (GHRP means growth hormone releasing hexapeptide, a type of growth hormone releasing hormone). This can be useful in a couple of ways.

Obviously an athlete will need to heal quickly and be productive soon after an injury. Peptides will help the muscle or soft tissue in this rebuilding healing process.

Supplements that provide an anabolic effect could also be used during preseason and other periods where building muscle mass is important.

Muscle mass can be built quickly because the athlete can make small tears in a muscle and have it heal on a rapid schedule to continuously repeat the process – the end effect being increased muscle mass and reduced body fat in a shorter time frame.

The bodybuilding community use peptides that are most effective in this second way as newer peptides don’t come with the side-effects of anabolic steroids.

It is the links to bodybuilding and gym communities that help pro-athletes find new substances such as peptides to improve performance.

For some time now, the bodybuilding community has been aware of these supplements and the inability for testing to detect them in most cases.

This is especially the case if urine testing is the main form of detection. Many peptides aren’t yet cleared for human use.

However, peptides are readily available on the sporting supplement market and aren’t very expensive.
They would have to be missing out on the biggest peptides boom in the history of the supplement industry with all the recent focus on their attributes.

Now we know what peptides are and what they can be used for.

The real issues are how many athletes have been using them and whether the ACC, ASADA and the police can catch the ones who have.

Tuesday, September 9, 2014

Effect of peptide hormone CJC-1295 in your body workout

CJC-1295 is basically a peptide hormone that acts similar to growth hormone releasing hormones (GHRH). It is beneficial to athletes because it can bioconjugate with circulating albumin and increase the time it can be used for medical purposes. It achieves this by preventing degradation of its amino acids. With a single dose, it can remain in the body for quite a few days and can cause the growth hormone to be released many times per day. This reduces the frequency of injections needed.CJC-1295 increases the production of growth hormone as well as IGF-1 – which has anabolic effects in adults. However, it does not increase the levels of prolactin – high levels of which can create impotence and mental health problems in men. By increasing these two hormones, it enhances protein production in the body, which in turn, boosts muscle mass. It also induces lipolysis – the breakdown of fat tissue, boosts recovery from injuries, increases bone density, and also reduces aging factors like skin wrinkles. It can also stimulate cell growth, due to which it can be used to treat withered tissue or organs.

CJC-1295 is also known by the names of Modified GRF 1-29, Mod GRF 1-29, CJC-1295 without DAC (DAC stands for Drug Affinity Complex) and also by its chemical name tetrasubstituted GRF (1-29). This variety of names makes it difficult for the average consumer to select or even research upon this compound. Since some manufacturers list all of its names and others list only one, it also becomes very confusing. However, there is a reason for this wide variety of names.

The original GRF (1-29) has a half-life of about 30 minutes. Half-life means the time within which half of the hormone administered will be destroyed within the body. This short half-life is due to the fact that the compound is highly unstable and breaks down soon. To increase its stability and to make it last longer, it was modified by adding 4 amino acids in its structure. This gave it the name Modified GRF (1-29) or Mod GRF 1-29. It was originally invented by DatBtrue. The portion of the molecule that actually stimulates the growth hormone secretion is found in the chain of 29 amino acids, so it is named GRF (1-29). This chemical also produces slow-wave sleep.

However, both the original GRF (1-29) and the Mod GRF 1-29 required frequent dosages. So a new compound called CJC-1295 was created which was far more stable. This compound was made by adding Lysine – which is a non-peptide, and is also called Drug Affinity Complex or DAC. Since the original Mod GRF 1-29 does not contain DAC, it is named as CJC-1295 without DAC. However, the actual CJC-1295 is not only difficult, but also very expensive to produce. This is why it is not produced or used extensively. The Mod GRF 1-29 is far easier and cheaper to produce. CJC-1295 acts for much longer than pure GRF. It acts on the pituitary gland and keeps stimulating the release of growth hormone in pulses. The reason why it acts in pulses is because the axis of the human growth hormone controls how much of the hormone can remain in the body at a time. This maintains the homeostatic environment in the body.

The DAC technology in the CJC-1295 enables the compound to bind itself covalently with any circulating albumin, after it has been administered through a subcutaneous injection. However, the reason why the half-life could be extended from a few minutes to several days is more profound. The reactive group in the CJC-1295 binds to a peptide through bioconjugation. The peptide then finds a neucleophilic unit within the blood and reacts with it in order to create a firmer bond.

When using any GHRH, it should always be remembered that positive results cannot be achieved overnight. These compounds act steadily over time, and the best results can be achieved slowly, and with a nutritious diet and a proper exercise regime. Also, these peptides are not sex-specific, so they do not have any androgenic effects. They can be used by women in the same dosages that men do. Mod GRF 1-29 and CJC-1295 are still being researched. As such, they are not yet medically utilized or approved. Though some firm protocols for the use of these peptides have been developed, the dosage of the compound is not yet medically confirmed. In a study conducted by researchers on 21 to 61 year-old subjects, it was found that depending on the dose, the concentrations of the growth hormone increased to up to 10 times for at least 6 days. Also, the concentration of IGF-1 increased to up to 3 times for 9 to 11 days.

CJC-1295 and Mod GRF 1-29 are administered in micrograms (mcg) rather than milligrams (mg) – the unit of administration of other steroids and performance-enhancing drugs. It has also been found that a 100mcg dose is enough to fully saturate the receptors in the anterior pituitary. This is called the saturation dose. After a dose of 100mcg has been administered, the subsequent dosages will achieve only half the effect.For example, if 100mcg more were to be administered after the first 100mcg (making the effective dose of 200mcg), then the second dose will achieve only 50% of what the first dose already did. A 100mcg more (making a total of 300mcg) will achieve only 25% more of the initial dose. This implies that, in order to increase the effect of the compound, only a little more of it can be successfully administered after the saturation dose.

Tuesday, September 2, 2014

Proviron (Mesterolone) effective anabolic steroid

Proviron (Mesterolone) an anabolic steroid, is particularly interesting. This drug has good binding to the androgen receptor, but in muscle tissue most of it never reaches the androgen receptor because it is enzymatically converted to the diol. Thus, it is not an effective anabolic. It is somewhat effective as an anti-gyno agent, however, and appears to reduce estrogenic bloating if that problem exists. Proviron reduces either levels of estrogen or the effect of estrogen. Thus, it is useful for avoiding gynecomastia, although it probably should not be relied upon as the sole drug for that. It is not hepatotoxic. It has the usual side effects of anabolic/androgenic steroids, with the added effect that it is particularly prone to cause erections.

Mesterolone is an orally active, 1-methylated DHT. Like Masteron, but then actually delivered in an oral fashion. DHT is the conversion product of testosterone at the 5-alpha-reductase enzyme, the result being a hormone that is 3 to 4 times as androgenic and is structurally incapable of forming estrogen. One would imagine then that Mesterolone would be a perfect drug to enhance strength and add small but completely lean gains to the frame. Unfortunately there is a control mechanism for DHT in the human body. When levels get too high, the 3alpha hydroxysteroid dehydrogenase enzyme converts it to a mostly inactive compound known as 3-alpha (5-alpha-androstan-3alpha,17beta-diol), a pro-hormone if you will. It can equally convert back to DHT by way of the same enzyme when low levels of DHT are detected. But it means that unless one uses ridiculously high amounts, most of what is administered is quite useless at the height of the androgen receptor in muscle tissue and thus Mesterolone is not particularly suited, if at all, to promote muscle hypertrophy.

Proviron has four distinct uses in the world of bodybuilding. The first being the result of its structure. It is 5-alpha reduced and not capable of forming estrogen, yet it nonetheless has a much higher affinity for the aromatase enzyme (which converts testosterone to estrogen) than testosterone does. That means in administering it with testosterone or another aromatizable compound, it prevents estrogen build-up because it binds to the aromatase enzyme very strongly, thereby preventing these steroids from interacting with it and forming estrogen. So Mesterolone use has the extreme benefit of reducing estrogenic side-effects and water retention noted with other steroids, and as such still help to provide mostly lean gains. Its also been suggested that it may actually downgrade the actual estrogen receptor making it doubly effective at reducing circulating estrogen levels.

The second use is in enhancing the potency of testosterone. Testosterone in the body at normal physiological levels is mostly inactive. As much as 97 or 98 percent of testosterone in that amount is bound to sex hormone binding globulin (SHBG) and albumin, two proteins. In such a form testosterone is mostly inactive. But as with the aromatase enzyme, DHT has a higher affinity for these proteins than testosterone does, so when administered simultaneously the mesterolone will attach to the SHBG and albumin, leaving larger amounts of free testosterone to mediate anabolic activities such as protein synthesis. Another way in which it helps to increase gains. Its also another part of the equation that makes it ineffective on its own, as binding to these proteins too, would render it a non-issue at the androgen receptor.

Thirdly, Mesterolone is added in per-contest phases to increase a distinct hardness and muscle density. Probably due to its reduction in circulating estrogen, perhaps due to the down regulating of the estrogen receptor in muscle tissue, it decreases the total water build-up of the body giving its user a much leaner look, and a visual effect of possessing "harder" muscles with more cuts and striations. Proviron is often used as a last-minute secret by a lot of bodybuilders and both actors and models have used it time and again to deliver top shape day in day out, when needed. Like the other methylated DHT compound, drostanolone, mesterolone is particularly potent in achieving this feat.

Lastly Proviron is used during a cycle of certain hormones such as nandrolone, with a distinct lack of androgenic nature, or perhaps 5-alpha reduced hormones that don't have the same affinities as DHT does. Such compounds, thinking of trenbolone, nandrolone and such in particular, have been known to decrease libido. Limiting the athlete to perform sexually being the logical result. DHT plays a key role in this process and is therefore administered in conjunction with such steroids to ease or relieve this annoying side-effect. Proviron is also commonly prescribed by doctors to people with low levels of testosterone, or patients with chronic impotence. Its not perceived as a powerful anabolic, but it gets the job done equally well if not better than other anabolic steroids making it a favorite in medical practices due to its lower chance of abuse.

Mesterolone is generally well liked nonetheless as it delivers very few side-effects in men. In high doses it can cause some virilization symptoms in women. But because of the high level of deactivation and per-destination in the system (albumin, SHBG, 3bHSD, aromatase) quite a lot of it, if not all simply never reaches the androgen receptor where it would cause anabolic effects, but also side-effects. So its relatively safe. Doses between 25 and 250 mg per day are used with no adverse effects. 50 mg per day is usually sufficient to be effective in each of the four cases we mentioned up above, so going higher really isn't necessary. Unlike what some suggest or believe, its not advised that Proviron be used when not used in conjunction with another steroid, as it too is quite suppressive of natural testosterone, leading to all sorts of future complications upon discontinuation. Ranging from loss of libido or erectile dysfunction all the way up to infertility. One would not be aware of such dangers because Proviron fulfills most of the functions of normal levels of testosterone.

Tuesday, August 26, 2014

STANOVER 10 (Stanozolol) by Vermodje

Stanozolol represent synthetic high anabolic steroid with androgenic proprieties. It is available both as oral compound and as water based injectable one.

The oral and injectable forms of this supplement are similar, that’s mean that effects and side-effects are the same, but in many cases bodybuilders noticed the injectable compound to be more efficient.

Usually by using STANOVER 10 (Stanozolol) bodybuilders or athletes will not report huge and dramatic gains, but achieved strength are quite dramatically.

Stanozolol is a DHT derived compound. Being 17-alpha-alkylated Stanozolol is toxic on liver, it can also negative affect the LDL/HDL ratio.
STANOVER 10 (Stanozolol) does not have the proprieties to convert to estrogen, that’s mean that it does not cause excess water retention and gynecomastia. So an anti estrogen product is not necessary whilst using this steroid.

One of the properties of this supplement is its characteristic to lower SHBG much more than other steroids.

STANOVER 10 (Stanozolol) represent a drug that in most cases is taken by bodybuilders/athletes in cutting cycles. Although, sometimes stanozolol is used by sportsmen as a bulking agent in combination with more androgenic drug like testosterone.

Bodybuilders, athletes must know that Stanozolol are detectable in the urine for up to 10 days.

Stanozolol is often chosen by female, instead of the fact that it provokes masculinization side effects, especially when it is taken at high dose. Effective dose are around 25-100 mgs day for male bodybuilders and 5-25 mgs day for women. STANOVER 10 (Stanozolol) by Vermodje is an anabolic steroid that contains an active substance named Stanozolol. It is commercialized in 10 ml vial and contains 50mg/ml of hormone.

STANOVER 10 (Stanozolol) is used in medicine for stimulating appetite and increasing weight gain, strength and vigor. Also it shows success in treating anemia and hereditary angioedema.

STANOVER 10 (Stanozolol) is popular between bodybuilders and is derivative of dihydrotestosterone. It is also known as Winstrol Depot. Being high anabolic steroid is characterized with low androgenic proprieties. Winstol do not aromatize and seldom produce water retention. It is also relatively toxic to the liver. This steroid stimulates the anabolic process and inhibits the catabolic once produced by the corticosteroids. A lot of athletes like to take this steroid because it help in fast muscle grow. Another thing that makes it loved by bodybuilders is that it improves the tissues nutrition and help depositing the calcium in the bones.

Winstrol Depot is often used in bodybuilding in cutting cycle. At the final phase of cutting cycle it is good to combine it with a non-aromatizing androgen such as Trenbolone or Halotestin. An efficient dose for men is 25-100 mg/day. It is recommended should be taken no more than 48 hours apart, with some users preferring to inject every day, or even twice a day, to maintain serum levels.

Female athletes are not really advised to take this steroid because they can notice virility symptoms, inhibition of the ovary function, disorders of menstrual cycle.

Other side effects that can appear are: gynecomastia, deepening of the voice, male pattern baldness, acne, hormonal disorders.

Diabetic patients, hepatic, renal or cardiac insufficiency people are advised to be careful and see the doctor before taking the decision to start taking it.

Wednesday, August 20, 2014

Androgel is an Anabolic Steroid

Many individuals suffer from low-testosterone, as we age our testosterone levels rapidly decline. In some cases these levels decline even more rapidly than what is considered Medically Acceptable and therapy is needed. There are several options for treatment of low-testosterone and Androgel has rapidly become one of the most popular.

Androgel has not risen in popularity because of its superiority over other types of testosterone medication but largely due to its convenience. Almost all medications used to treat low-testosterone must be injected, however Androgel is a topical solution that only needs to be rubbed into the skin and allowed to absorb into the body. There is however an inconvenience factor that exist; with injectable testosterone used to treat low-testosterone, injections are typically administered every ten to fourteen days but Androgel must be administered every single day in order to reap benefits as well as maintain proper testosterone levels.

Many men notice as they age it becomes increasingly difficult to maintain a healthy body weight, muscle tissue and mass decline, body-fat increases and energy levels decline. There's no doubt these symptoms mentioned can largely be improved by diet and exercise but studies have shown a larger problem is often a decline in natural testosterone levels. Beyond the symptoms listed, another prominent symptom and a quite unwelcomed one is lower than normal to even non-existent sex drive. If you suffer from any of these symptoms there is a good chance your natural testosterone levels are low and Androgel may indeed remedy this problem. However this will only be determined by your doctor through a series of test and if testing shows a low level of testosterone there's a good chance a prescription of Androgel will be in your future.

As most understand, anabolic steroids have a bad reputation but unknown by most who use Androgel they are surprised to know they're actually using anabolic steroids. Granted, when you use Androgel the actual amount used will be far less than whats typically used in the performance enhancing world. For example; most who use exogenous testosterone for performance enhancing purposes will at minimum inject approximately 500mg per week. Contrary, Androgel which is also a testosterone medication is given in far higher doses but absorbed in a far lower concentration. Common Androgel doses generally range in the 5g to 10g range, this is five to ten times the amount of testosterone used by performance enhancers at the lowest level. However, with the use of Androgel only ten percent of the drug is absorbed in a usable fashion, the rest of the medication is simply wasted. There's no doubt about it, if you suffer from low-testosterone Androgel therapy will greatly improve your life and overall well-being, but understand the benefits are not going to be comparable to the use of other common anabolic steroids; including injectable testosterone.

Wednesday, August 13, 2014

The Benefits of Sustanon-250

Sustanon injection contains testosterone esters. These are derivatives of the naturally occurring male hormone testosterone. They are converted in the body to testosterone.

Testosterone is known as an androgen. It is produced by the testicles and is the main hormone essential for normal growth and development of the male sex organs and male sexual characteristics.

The natural production of testosterone is controlled by another set of hormones called gonadotrophins, which are released from the pituitary gland in the brain.

During adult life, testosterone is essential for the production of sperm, the maintenance of sex drive, erectile potency, and the functioning of the prostate gland and other reproductive structures. It also has functions in the skin, muscles, skeleton, kidney, liver, bone marrow and central nervous system.

Low levels of testosterone can cause decreased sex drive, impotence, infertility due to decreased sperm production, decreased mental and physical activity, fatigue and weakening of bones.

Testosterone is given as replacement therapy when natural testosterone levels fall too low, causing symptoms such as those above. Natural testosterone levels fall with age and following surgical removal of the testicles (castration). They may also fall due to decreased functioning of the testicles (hypogonadism or eunuchoidism) caused by testicular disease, or by decreased gonadotrophin production by the pituitary gland, as a result of pituitary disease.

Testosterone replacement allows natural testosterone levels to return to normal, thus relieving the symptoms of the deficiency.

Sustanon injection is called a depot injection. It is injected slowly into the muscle where it forms a reservoir of medicine. The testosterone is gradually released all the time from the reservoir into the bloodstream. The injection is usually given once every two to three weeks, though the frequency will depend on your individual testosterone levels. Sustanon-250 is the brand name for the four part testosterone mixture originally created by Organon but as is common, as it was the first form of the compound the trade name Sustanon-250 is largely associated with all brands. Sust, as it is commonly known is comprised of only testosterone but it has four various esters attached; two short, one moderate and one long ester. The composition of the compound is as follows:

    Testosterone Propionate: 30mg
    Testosterone Phenylpropionate: 60mg
    Testosterone Isocaproate: 60mg
    Testosterone Decanoate: 100mg

To understand Sustanon-250 we only need to understand testosterone and the manner in-which esters work. Once we understand the hormone testosterone and once we understand the esters attached are not hormones then we can understand how this particular steroidal compound is supposed to work.

As you can see from its makeup a large portion of the testosterone becomes active very quickly once administered due to the Propionate and Phenylpropionate forms being attached. However, the full release will not occur until the Decanoate fulfills its function; because of the Decanoate ester being attached Sustanon-250 has a total half-life of approximately 18 days.

The greatest benefit of use is by far the ability to provide testosterone over an extended period of time but for the performance enhancer this proves to be of little use. When used for performance purposes the idea is not to simply provide testosterone but to do so and keep it at its peak level as well as stable. Due to this fact and since Sustanon-250 provides a dose that dwindles as time goes by for performance purposes it must be injected at minimum every three days with every other day being optimal.

Once you understand the manner in-which best suits your needs in-terms of injection frequency you can then enjoy the benefits of this powerful testosterone hormone. Like all testosterone's, regardless of the form, Sustanon-250 will greatly increase nitrogen retention in the muscles as well as protein synthesis; key factors in both growth and preservation. Further, through testosterone use we can readily increase our red blood cell count and the powerful anabolic IGF 1 hormone, all key factors in the performance game.

Tuesday, August 5, 2014

Oxytocin Hormone

Oxytocin is a mammalian hormone that acts primarily as a neuromodulator in the brain. Oxytocin is best known for its roles in sexual reproduction, in particular during and after childbirth. It is released in large amounts after distension of the cervix and uterus during labor, facilitating birth, and after stimulation of the nipples, facilitating breastfeeding. The word Oxytocin was derived from the greek word“, meaning quick birth. The Oxytocin peptide is synthesized as an inactive precursor protein from the OXT gene.

Oxytocin is a peptide of nine amino acids (a nonapeptide). Its systematic name is cysteine-tyrosine-isoleucine-glutamine-asparagine-cysteine-proline-leucine-glycine-amine. The cysteine residues form a disulfide bond. Oxytocin has a molecular mass of 1007 daltons. One international unit (IU) of Oxytocin is the equivalent of about 2 micrograms of pure peptide. The trust-inducing property of oxytocin might help those who suffer from social anxieties and mood disorders, but with the potential for abuse with confidence tricks and military applications.

The structure of oxytocin is very similar to that of vasopressin, also a nonapeptide with a sulfur bridge, whose sequence differs from Oxytocin by two amino acids. Oxytocin and vasopressin were isolated and synthesized by Vincent du Vigneaud in 1953, work for which he received the Nobel Prize in Chemistry in 1955. Oxytocin and vasopressin are the only known hormones released by the human posterior pituitary gland to act at a distance. However, Oxytocin neurons make other peptides, including corticotropin-releasing hormone and dynorphin, for example, that act locally. Oxytocin has peripheral (hormonal) actions, and also has actions in the brain. Its actions are mediated by specific, high-affinity oxytocin receptors. The oxytocin receptor is a G-protein-coupled receptor that requires Mg2+ and cholesterol. Oxytocin is destroyed in the gastrointestinal tract, so must be administered by injection or as nasal spray. It has a half-life of typically about three minutes in the blood, and given intravenously does not enter the brain in significant quantities - it is excluded from the brain by the blood-brain barrier. Evidence in rhesus macaques indicates Oxytocin by nasal spray does enter the brain. Oxytocin nasal sprays have been used to stimulate breastfeeding, but the efficacy of this approach is doubtful.

In the hypothalamus, Oxytocin is made in magnocellular neurosecretory cells of the supraoptic and paraventricular nuclei and is stored in Herring bodies at the axon terminals in the posterior pituitary. Oxytocin is also made by some neurons in the paraventricular nucleus that project to other parts of the brain and to the spinal cord. Depending on the species, Oxytocin receptor-expressing cells are located in other areas, including the amygdala and bed nucleus of the stria terminalis. In the pituitary gland, Oxytocin is packaged in large, dense-core vesicles, where it is bound to neurophysin I. Secretion of Oxytocin from the neurosecretory nerve endings is regulated by the electrical activity of the oxytocin cells in the hypothalamus.

Outside the brain, Oxytocin containing cells have been identified in several diverse tissues, including the corpus luteum, the interstitial cells of Leydig, the retina, the adrenal medulla, the placenta, the thymus and the pancreas. The finding of significant amounts of this classically "neurophysiology" hormone outside the central nervous system raises many questions regarding its possible importance in these different tissues. The Leydig cells in some species have also been shown to possess the bio-synthetic machinery to manufacture testicular Oxytocin de novo, to be specific, in rats (which can synthesize vitamin C endogenously) and in guinea pigs, which, like humans, require an exogenous source of vitamin C (ascorbic).