Tuesday, December 16, 2014

Deca Durabolin Effect in bodybuilding

This is an injectable steroid that is a derivative of 19-nortestosterone. It is one of the most popular steroids of all time. Deca is a low androgenic steroid, with high anabolic properties. It is used for developing size and strength. It does not have very high liver toxicity nor does it disturb the body’s own hormone functions too excessively at low doses. Deca Durabolin is a 19-Nor compound (some would say that it is the 19-nor compound), and as such, it shares basically the same characteristics with all of them. One thing unique to Deca, above nearly all steroids, is the mystique it has had for the last quarter of a century. On a personal level, Ive included Deca in cycles at doses ranging from 100mgs/week to 2,000mgs per week. For many, this was and is the final word on Deca. Lets delve into some of the reasons that Deca's mystique may be well deserved. Nandrolone is by far one of the most popular anabolic steroids available. This is due to the compound's affinity for being highly anabolic but relatively mild in terms of androgenic side effects. Nandrolone is the base steroid 19Nor-testosterone, meaning that it is like testosterone in appearance except for the absence of a carbon atom in the 19th position. This small change makes a major difference in the characteristics of the compound. Notably, this change makes Nandrolone a less potent agonist of the androgen receptor. This of course reduces the chance that a user will experience androgenic side effects. Instead of forming Dihydrotestosterone when encountering the 5 alpha reductase enzyme like testosterone does, Nandrolone will form dihydronandrolone. Dihydronandrolone is extremely mild in terms of it's antagonizing the androgen receptor. Therefore androgenic side effects should be far less likely to occur with Nandrolone than with testosterone. It is of note however that Nandrolone is believed to have some activity as a progestin in the body. Although progesterone is a c-19 steroid, removal of this group as in 19-norprogesterone creates a hormone with greater binding affinity for its corresponding receptor. The compound will stimulate the progesterone receptor, along with progesterone. Side effects associated with this activity are similar to some of those related to estrogenic ones including water retention, acne, and gynecomastia among others. However these side effects are fairly rare in comparison to more androgenic compounds.

First of all, Deca Durabolin (and Nandrolone in general) doesn't produce many estrogenic or androgenic side effects. This is because Deca Durabolin has a very low rate of aromatization (conversion to estrogen via the aromatase enzyme), roughly equal to 20% the rate of Testosterone. Deca will aromatize in higher dosages, but not at the rate of testosterone’s or other high androgenic compounds. This drug can be used for cutting or for bulking. Athletes have stacked it with virtually every drug. It is a good base drug on any cycle. Deca is said to have the best effect to side effect ratio of any other steroid.

Women use this drug but only in very low dosages, 25mg per week. Deca has been established as a great soother of sore joints and tendons. Athletes report that sore shoulders, knees, and/or elbows are somehow without pain on the Deca cycle. This may be substantiated by proving it reduces the amount of cortisol getting into muscle tissue during the cycle. Deca also dramatically improves nitrogen retention and recuperation time between workouts. Deca has shown up positive on more steroid tests than any other steroid. This is due to the fact that so many athletes use it, and that it stays in the system at a detectable level for up to a year. The higher the fat content of the user, the longer it stays in your system. Deca can be active from 10-14 days after injection, but weekly injections of 300-600 mgs are common for men. Deca, or more precisely Nandrolone Decanoate, is commonly counterfeited.

Endocrine and Metabolic:
Endocrine side effects noted during exogenous administration of anabolic steroids have included inhibition of endogenous testosterone release by means of feedback inhibition of pituitary luteinizing hormone (LH). Large doses of exogenous anabolic steroids may suppress spermatogenesis through inhibition of pituitary follicle stimulating hormone (FSH). The androgenic activity of anabolic steroids may decrease levels of thyroid-binding globulin and result in decreased total T4 serum levels and increased resin uptake of T3 and T4. Free thyroid hormone levels remain unchanged and there is no clinical evidence of thyroid dysfunction.
Metabolic effects occurring during anabolic steroid therapy in immobilized patients or those with metastatic breast disease have included osteolytic-induced hyperglycemia. Anabolic steroids affect electrolyte balance, nitrogen retention, and urinary calcium excretion. Edema, with and without congestive heart failure, has occurred. Decreased glucose tolerance requiring adjustments in hyperglycemia control has been noted in diabetic patients. Significant increases in low density lipoproteins (LDL) and decreases in high density lipoproteins (HDL) have occurred.

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