Wednesday, November 26, 2014

Somatotropic Hormone and bodybuilding

The growth hormones is a polypeptide hormone consisting of 191 amino acids. In humans it is produced in the hypophysis and released if there are the right stimuli (e.g. training, sleep, stress, low blood sugar level). It is now important to understand that the freed HGH (human growth hormones) itself has no direct effect but only stimulates the liver to produce and release insulin-like growth factors and somatomedins. These growth factors are then the ones that cause various effects on the body. The problem, however, is that the liver is only capable of producing a limited amount of these substances so that the effect is limited. If growth hormones are injected they only stimulate the liver to produce and release these substances and thus, as already mentioned, have no direct effect.

The use of these STH somatotropic hormone compounds offers the athlete three performance-enhancing effects. STH (Somatotropic Hormone) has a strong anabolic effect and causes an increased protein synthesis which manifests itself in a muscular hypertrophy (enlargement of muscle cells) and in a muscular hyperplasia (increase of muscle cells.) The latter is very interesting since this increase cannot be obtained by the intake of steroids. This is probably also the reason why STH is called the strongest anabolic hormone. The second effect of STH is its pronounced influence on the burning of fat. It turns more body fat into energy leading to a drastic reduction in fat or allowing the athlete to increase his caloric intake. Third, and often overlooked, is the fact that STH strengthens the connective tissue, tendons, and cartilages which could be one of the main reasons for the significant increase in strength experienced by many athletes. Several bodybuilders and powerlifters report that through the simultaneous intake with steroids STH protects the athlete from injuries while increasing his strength.

There are three hormones which are needed at the same time in order to allow for maximum anabolic effect. These are STH, insulin, and an LT-3 thyroid hormone, such as, for example, Cytomel. Only then can the liver produce and release an optimal amount of somatomedin and insulin-like growth factors. This anabolic effect can be further enhanced by taking a substance with an anticatabolic effect. These substances are-everybody should probably know by now-anabolic/androgenic steroids or Clenbuterol. Then a synergetic effect takes place.'Are you still wondering why pro bodybuilders are so incredibly massive but, at the same time, totally ripped while you are not. Most athletes have tried STH during preparation for a competition in that phase when the diet is calorie-reduced.  The body usually reacts by reducing the release of insulin and of the L-T3 thyroid hormone.  Those who combine Clenbuterol with STH, should know that Clenbuterol (like Ephedrine) reduces the body's own release of insulin and L-T3. True, this seems a little complicated and when reading it for the first time it might be a little confusing; however it really is true: STH has a significant influence on several hormones in the human body; this does not allow for a simple administration schedule. Since most athletes vho want to use STH can only obtain it if prescribed by a physician, the only supply source remains the black market. And this is certainly another reason why some athletes might not have been very happy with the effect of the purchased compound. In addition to a display of labels in the Dutch or Russian language the fakes are distinguished from the original product, in sofar as the dry substance is not present as lyophilic but present as loose powder. Nowhere can this much money be made except by faking STH. Who has ever held original growth hormones in his hand and known how they should look?. In a few very rare cases the body reacts by developing antibodies to the exogenous STH, thus making it ineffective. The question of the right dosage, as well as the type and duration of application, is very difficult to answer. Since there is no scientific research showing how STH should be taken for performance improvement, we can only rely on empirical data, that is experimental values. The respective manufacturers indicate that in cases of hypophysially stunted growth due to lacking or insuffieient release of growt hormones by the hypophysis, a weekly average dose of 0.3 I.U/ week per pound of body weight should be taken. An athlete weighting 200 pounds, therefore, would have to inject 60 I.U. weekly. The dosage would be divided into three intramuscular injections of 20 I.U. each. Subcutaneous injections (under the skin) are another form of intake which, however would have to be injected daily, usually 8 I.U. per day. Top athletes usually inject 4-16 I.U./day. Ordinarily, daily subcutaneous injections are preferred. Since STH has a half life time of less than one hour, it is not surprising that some athletes divide their dail dose into three or four subcutaneous injections of 2-4 I.U. each. Application of regular small dosages seems to bring the most effective results. This also has its reasons: When STH is injected, serum concentration in the blood rises quickly, meaning that the effect is almost immediate. As we know, STH stimulates the liver to produce and release somatomedins and insulin like growth factors which in turn effect the desired results in the body. Since the liver can only produce a limited amount of these substances, we doubt that larger STH injections will induce the liver to produce instantaneously a larger quantity of somatomedins and insulin-like growth factors. It seems more likely that the liver will react more favorably to smaller dosages. If the STH solution is injected subcutaneously several consecutive times at the same point of injection, a loss of fat tissue is possible. Therefore, the point of injection, or even better, the entire sisde of the body should be continuously, changed in order to avoid a loss of local fat tissue (lipoathrophy) in the injection cell. One thing has manifested itself over the years: The effect of STH is dosage-dependent. This means either invest a lot of money and do it right or do not even begin. Half-hearted attempts are condemned to failure Minimum effective dosages seem to start at 4 I.U. per day. For comparison: the hypophysis of a healthy, adult, releases 0.5-1.5 I.U. growth hormones daily.

Our experience is that STH is taken over a prolonged period, from at least six weeks to several months. It is interesting to note that the effect of STH does not stop after a few weeks; this usually allows for continued improvements at a steady dosage. Bodybuilders who have had positive results with STH have reported that the build-up strength and, in particular, the newly-gained muscle system were essentially maintained after discontinuance of the product. It remains to be clarified what happens with the insulin and LT-3 thyroid hormone. Athletes who take STH in their build-up phase usually do not need exogenous insulin. It is recommended, in this case, that the athlete eats a complete meal every three hours, resulting in 6-7 meals day. This causes the body to continuously release insulin so that the blood sugar level does not fall too low. The use of LT-3 thyroid hormones, in this phase, is carried out reluctantly by athletes. In any case, you must have a physician check the thyroid hormone level during the intake of STH. Simultaneous use of anabolic /androgenic steroids and/or Clenbuterol is usually appropriate. During the preparation for a competition the use of thyroid hormones steadily increases.

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