Friday, February 6, 2015

Powerful anabolic steroid Drostanolone Propionate

Masteron is a modified form of Dihydrotestosterone, with a methyl group at the 2nd carbon (carbon alpha) atom. This modification is responsible for the anabolic strength increase. This methyl group makes it harder for the enzyme 3-hydroxysteroid dehydrogenase to metabolize Masteron. This enzyme is abundantly present in muscle tissue, and is responsible for degrading any DHT into two inactive metabolites: 3-Alpha Androstanediol and 3-Beta Androstanediol. Because of this enzyme DHT is not anabolic in muscle tissue at all. It is believed that if the enzyme 3-hydroxysteroid dehydrogenase was neutralized, DHT would actually be a very powerful anabolic steroid. Drostanolone's methyl group addition makes it imune to this enzyme. 

Drostanolone is injected into the body as an ester (bonded to either Propionate or Enanthate). Enzymes cleave off the ester from the Masteron molecule - which takes varying amount of time depending on which ester was used. This process causes the gradual release rate and extended half-life of the steroid. Drostanolone Propionate has a half-life of 2.5 days, while Drostanolone Enanthate has a half-life of 10 days. 

Intended use of Drostanolone / Masteron:  
Masteron was initially marketed as a treatment of female breast cancer. Because it pronounced male characteristics in women and because more effective breast cancer treatments were invented, Drostanolone was gradually phased out.

Actual use of Masteron:
Nowadays Drostanolone is a very popular anabolic steroid used mainly by athletes and bodybuilders.

Like other steroids Masteron can be injected into any muscle (if the muscle is big enough). The most popular being buttocks, shoulders and triceps. 

Masteron cycle compatibility, examples and duration 

Like majority of steroids, Masteron acts very well in combination with Human Growth Hormone (4IU per day). 

Effects of Drostanolone / Masteron (desirable) 

There are principally two desirable effects of Testosterone: 
physical / athletic performance enhancement (endurance, strength, faster regeneration)  physique enhancement (muscle buildup, fat loss)
The rest of desirable testosterone effects that an individual might experience during the steroid cycle, include:  increase in collagen synthesis and bone mineral content. Collagen is the protein-based construction material for connective tissues throughout the body (the ligaments, tendons, cartilage, joints, and bones).

Masterone or Drostanolone is an anabolic androgenic steroid that has been successfully used as a breast cancer drug. This anabolic androgenic steroid is commonly used by athletes who want to retain strength and muscle mass while losing fat. Also used in the bodybuilding community as a muscle defining drug and diuretic, this steroid can increase muscle hardness and density in a short period of time to give a more complete appearance to users, when preparing for bodybuilding contests. 

Masteron is available in two forms: Masteron propionate and Masteron enanthate. The primary difference between these two is that while the enanthate version is slow but long acting, the propionate version is fast and is required to be injected every other day.

Masteron propionate (or Drostanolone propionate) is perhaps one of the more "exotic" anabolic androgenic steroids in today's online market. It can be purchased, with or without a medical prescription, in different forms like capsules, tablets, sprays, or injections. Masteron propionate has a half life of 1-2 days.

Commonly used as a cutting or pre-contest drug, its use is associated with improvements in terms of aggression, performance, stamina, muscle size, and muscle function. This derivative of Dihydrotestosterone (DHT) blocks the conversion of free testosterone to estrogen by the aromatization pathway by inhibiting the aromatase enzyme. As a result, Masteron marginally increases the amounts of active free testosterone in circulation and negate the side effects of high estrogen levels because of aromatization.

One of the biggest advantages associated with use of this steroid is that it promotes strength gains while keeping body fat the same or even lowering it to prevent muscle loss while dieting. This advantage proves extremely advantageous for athletes in sports that have weight classes to improve performance, without the risk of being raised into a higher weight class. Masteron, an excellent cutting steroid, has recently become very popular in the underground market due to its efficacy and safety quotients compared to other steroids on sale.

Undoubtedly one of the most popular bodybuilding steroids of all time, Drostanolone Propionate has the ability to reduce estrogen in the body to a great extent. This steroid has a dramatic hardening effect on a lean physique and promotes greater metabolic activity and is most effective when used by athletes already in a lean state or when the level of body fat is already low. Masteron does not aromatize in the first place but may weaken the aromatase effect of many other anabolic steroids. Masteron inhibits water retention and athletes and bodybuilders using this drug can feel tight and very full after using it to experience "muscle pumps" like never before in the gym. In addition to these advantages, Masteron is also useful to accentuate fine details of muscles like striations.

The recommended dose of Masteron propionate for men is 500-700mg every week. This steroid is best stacked with Anadrol, Testosterone propionate, Dianabol, and Trenbolone acetate. This anabolic steroid may be stacked with Clenbuterol, Ephedrine, T3, Winstrol, and even Growth hormone or IGF-1. 

Masteron enanthate, which is also known as Drostanolone enanthate, has the chemical name of 17beta-Hydroxy-2alpha-methyl-5alpha-androstan-3-one Enanthate. This steroid has an active life of nearly eight to nine days and can be detected for up to several weeks. It has an anabolic androgenic rate of 62:25.

This steroid provides an aesthetic enhancement effect and is considered by bodybuilders as one of the best steroids to reduce any possible subcutaneous water retention that may obscure the view of muscle mass underneath. It also enhances bioavailability of other steroids in an anabolic steroid cycle through its anti-estrogen and anti-aromatase effects and preventing a measurable amount of SHBG (Sex Hormone Binding Globulin) from binding to other anabolic steroids and rendering them inactive. This anabolic androgenic steroid is best used for its ability to inhibit the transformation of free testosterone to estrogen and thereby enhancing the rate of free testosterone circulating in the body. The recommended dosage of Masteron enanthate is 400-600 mg weekly for men and 100 mg weekly for females and can be stacked with Trenbolone Enanthate, Clenbuterol, Ephedrine, T3, IGF-1, and Testosterone.

Masteron, available in oral and injectable forms, is not recommended to those suffering from health problems like testicular atrophy, testicular cancer, prostate cancer, breast cancer, liver damage, kidney damage, stroke, high blood pressure, and respiratory problems. The use of Masteron enanthate or propionate is also not advised for girls and women, especially who are pregnant, breastfeeding, or may get pregnant while using it. It is also not advised for children or those diagnosed with hypertension, high blood pressure, and prostate or breast cancer or those treated for health conditions such as testicular atrophy, testicular cancer, liver damage, kidney damage, stroke, and respiratory problems.

When abused or overdosed, Masteron can lead to oily skin, acne, body/facial hair growth, deepening of the voice, and hair loss. It may even cause increased sebum secretion (oily skin), increased bouts of acne (associated with increased sebum secretion), bodily and facial hair growth, and the increased risk of male pattern baldness. In women, Masteron can cause side effects like development of male secondary sex characteristics such as deepening of the voice, growth of body and facial hair), clitoral enlargement, and menstrual irregularities. Abuse of this steroid can even lead to suppression of the HPTA (Hypothalamic Pituitary Testicular Axis) and natural endogenous Testosterone production. Therefore, the use of post cycle therapy drugs like Clomid or Nolvadex is highly recommended to restore the normalization of the HPTA and endogenous Testosterone production as quickly as possible.

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