The Importance of Testosterone

The principal androgen (male sex hormone) is testosterone. This steroid is manufactured by the interstitial (Leydig) cells of the testes. Secretion of testosterone increases sharply at puberty and is responsible for the development of the so-called secondary sexual characteristics (e.g., beard) of men. The level of testosterone is under negative-feedback control: a rising level of testosterone suppresses the release of GnRH from the hypothalamus. This is exactly parallel to the control of estrogen secretion in females.

The Facts: Andropause, also known as the male menopause or manopause, is the result of a gradual drop in testosterone which is an androgen, giving the condition its name. In many cases, bioidentical hormones can be part of the solution. When men get into their early 30s, they begin losing testosterone at a rate of one to two percent a year.

The Importance of Testosterone: Testosterone assists the male body in building protein and is crucial for normal sexual drive and stamina, and in producing erections. Testosterone also contributes to several metabolic functions including bone formation, liver function, prostate gland growth and production of blood cells in bone marrow. The various studies suggest that using more than one type of anabolic steroid at the same time ("stacking") causes a stronger inhibition of the gonadal functions than using one single anabolic steroid. After abstention from anabolic steroids these changes in fertility usually reverse within some months. However, several cases of have been reported in which the situation of hypogonadism lasted for more than 12 weeks.