How to use Cytomel and HGH in bodybuilding

Cytomel is a thyroid hormone supplement that contains liothyronine. Liothyronine is a synthetic form of the hormone T3, which is naturally produced by the thyroid gland. This medication is given when the body does not produce enough of the hormone T3 on its own, a condition known as hypothyroidism.

Human growth hormone is naturally produced by the anterior lobe of the pituitary gland. There are HGH medications available by prescription for those with kidney failure, Turner's syndrome or other diseases. HGH medications, such as somatropin, humatrope, norditropin, are only not available in pill form, they come as injections. The DEA also states, " HGH is only bio available in the injectable form. The HGH molecule is too large for absorption across the lining of the oral mucosa and the hormone is digested by the stomach before absorption can occur."

Both Cytomel and HGH are hormones that are used for medical reasons to regulate growth in individuals whose bodies do not produce enough of these hormones naturally. When a person needs the medication Cytomel, she most likely has an underactive thyroid and she will gain weight, according to the Mayo Clinic. When a person needs an HGH medication, his body is not growing enough. Cytomel is liothyronine, a man-made medication designed to mimic the action of the T3 that is naturally produced by the thyroid gland. Somatropin is an injectable form of the HGH produced by the pituitary gland.

Cytomel up-regulates the beta-2 adrenergic receptors in fat tissues. In lipolysis, or the breakdown of fat in fat tissues, the enzyme HSL (hormone sensitive lipase) plays a significant part. HSL controls the rate of lipolysis. For HSL to be activated, epinephrine and nonepinephrine (catecholomines) are necessary. These catecholomines bind to the beta-2 receptors, and thus when Cytomel up-regulates the beta-receptors, there is a corresponding increase in the ability of catecholomines to activate HSL, resulting to increased lipolysis.

This drug is likewise known to increase the UCP-3 or uncoupling protein-3. This process significantly increases lipolysis. Further, Cytomel also stimulates growth hormone (GH) production, as substantiated by several studies. And since GH is a thermogenic, it contributes to this drug’s fat-burning action. This is why when athletes are using Cytomel they find no need to use HGH. With AAS use, the suppression occurs even after the therapy is stopped, sometimes in periods of weeks or months (especially in cases of long-term use). The same thing is observed during insulin intake, whereby the pancreas (the organ responsible for insulin production) ceases its production of insulin. Such is not the case with exogenous T3 hormone therapy. Several studies have concluded that thyroid therapy does not cause prolonged suppression of thyroid normal production. Thyroid function is normalized just days after medication is discontinued. In other words, there is no thyroid shutdown due to T3 supplementation; there is only a down-regulation of thyroid output during therapy.

Side effects of this class of drug include tachycardia and atrial arrhythmia, bone resorption, and loss of lean muscle tissue. Secondary side effects include insomnia, diarrhea, and nausea. These adverse reactions are highly possible if the user takes high dosages. Notice that some of its major side effects relate to the cardiovascular system. This is because thyroid hormones have significant effects on cardiac structures (including cardiac muscles) and systems that alter cardiovascular hemodynamics. Hyperthyroidism increases virtually all cardiac functions including heart rate and contractility, diastolic relaxation, and rate of ventricular pressure development. This results to an increased cardiac output by as much as 250 percent. These physiological changes are (most likely) the consequences of an increase in the expression of ATP and a decrease in the expression of ATP’s inhibitor, phospholamban.

Another drawback of Cytomel is its catabolic ability. When Cytomel exerts this ability on stored fats, this is an asset. However, this becomes a liability when it exerts this on bones and muscles. The negative result is bone resorption and muscle wasting (mentioned above). Moreover, this drug also diminishes GH’s nitrogen retention ability (although it stimulates GH’s production, as mentioned earlier). There is consensus among Cytomel users that the dosage protocol with this drug is to ramp it up, which means you start at the lowest dosage then gradually move upward. However, there are divergent opinions on how long the ‘gradually’ part should be. There are those who say it should be every three days, and then some pharmacological studies endorse it from 1 to 2 weeks. However, the user’s tolerance level ultimately determines the time frame; that is, if the user reacts really well with Cytomel, then the dosage can gradually increase every three days. Users are advised not to ramp up and down the dosage during therapy as this causes fluctuations in hormone levels, which further results to hormonal imbalance. The more prudent practice is to taper off the dosage. The minimum daily dosage of T3 is 5mcg and the maximum is 100mcg.

Cytomel intake is not dependent on body weight or gender, but rather on the individual’s blood level. This means that females can take the same dosage volume and schedule as males.

Why do some athletes use human growth hormones?

Human growth hormone (HGH), Insulin-Like Growth Factor (IGF-1) and insulin may stimulate muscle and bone development, in addition to breaking down fat.

HGH helps children grow and develop normally. Adults who take artificial HGH experience increased muscle mass, bone mass and bone strength. HGH also helps break down fat cells, leading to easier weight control. Some athletes are especially fond of HGH because it's very hard to detect. However, its side effects include acromegaly, enlarged internal organs and heart problems.

IGF-1 increases HGH's effectiveness. Like HGH, IGF-1 increases muscle mass and bone mass, and it also breaks down fat. However, IGF-1 can cause hypoglycemia. Insulin is a hormone normally produced by the body. If insulin is combined with HGH or other steroids, it can stimulate muscle development. As with IGF-1, insulin can cause hypoglycemia, which can be associated with shaking, nausea and weakness. Extreme hypoglycemia can induce a coma, and can even cause death.Human growth hormone (HGH), Insulin-Like Growth Factor (IGF-1) and insulin may stimulate muscle and bone development, in addition to breaking down fat.

HGH helps children grow and develop normally. Adults who take artificial HGH experience increased muscle mass, bone mass and bone strength. HGH also helps break down fat cells, leading to easier weight control. Some athletes are especially fond of HGH because it's very hard to detect. However, its side effects include acromegaly, enlarged internal organs and heart problems.

IGF-1 increases HGH's effectiveness. Like HGH, IGF-1 increases muscle mass and bone mass, and it also breaks down fat. However, IGF-1 can cause hypoglycemia. Insulin is a hormone normally produced by the body. If insulin is combined with HGH or other steroids, it can stimulate muscle development. As with IGF-1, insulin can cause hypoglycemia, which can be associated with shaking, nausea and weakness. Extreme hypoglycemia can induce a coma, and can even cause death.

Growth hormone and exercise:
The effect of acute exercise on production of HGH in the body has been widely described in the literature. The concentration of HGH in blood increases with time for a given work intensity and can increase 10‐fold during prolonged moderate exercise. During more intensive exercise (with accumulation of lactate at 70% Vo2 max for a short term period such as 10–20 minutes) HGH will increase by 5–10‐fold. With short exercise durations, levels of GH will generally peak at 15–30 minutes after the exercise. Furthermore, it appears that hGH response is more closely related to the peak intensity of exercise than the total work output. Endurance training generally amplifies the pulsate release of growth hormone, elevating the GH amplitude. This appears evident when the training is very hard and above the aerobic threshold.

Apart from exercise related increase, hGH secretion can be affected by other factors—for example, GH secretion is increased in hypoglycaemia, increased temperature, and stress, whereas it decreases in obesity, or with a carbohydrate‐rich diet and intake of β2 adrenergic agonists. Thus, it is hard to differentiate between the physiological increase in HGH levels seen in exercise and what can be from external HGH administration (as in doping). This problem makes the purely quantitative approach of measuring directly the total circulating GH not feasible in case of doping, except if the conditions of collection of biological samples are well controlled.

Human growth hormone for building muscle

Human growth hormone was initially designed in the 1920s to help children who had stunted growth. The pituitary glands of cadavers were ground up and injected into these children, which led to standard growth. It has since evolved into a material used for losing weight, slowing the aging process and mostly for building muscle.
Normally, HGH rises in humans into the mid-20s, then begins to fall, reaching about one-fifth of its peak value in the 70s.
An insulin tolerance test, ITT, performed by a doctor can measure whether grown up patients are suffering from a deficiency of HGH production. For patients who cannot stand for an ITT, an Arginine + GHRH test may be used. A baseline blood level of IGF-1 should also be performed.
According to the Human Growth Substructure, an estimated 15,000 children suffer in one configuration or another from a human growth hormone deficiency. Growth hormones are part of the human endocrine system, or the organization governing hormones. The chief operator of the endocrine system is the pituitary gland. The pituitary gland controls releases of growth hormones, which awaken cell reproduction. There are two main types, being sum total and partial. In a total deficiency there is no growth hormones created. In a partial deficiency, there are few hormones being secreted by the pituitary gland. A deformity in the pituitary gland will indubitably be a culprit in these types of deficiencies. According to the Human Growth Basis, hypopituitarism may be the leading cause in most deformities. Hypopituitarism occurs when a tumor, benign or malignant, presses on the hypothalamus or the pituitary gland, resulting in a sort of malfunction of the gland's everyday tasks.