Benefits of oral steroid Proviron

Proviron (or Mesterolone) is an oral Dihydrotestosterone-steroid compound similar to Masteron. It is admired for its ability to balance a deficiency of androgen formation that tends to fall gradually with increasing age. This anabolic androgenic steroid is medically prescribed for treatment of all conditions caused by deficient endogenous androgen formation. The IUPAC name of Proviron is 1 alpha-methyl-17 beta-hydroxy-5 alpha-androstan-3-one and the molecular mass of this prescription drug is 304.467 g/mol at the base. It has the molecular formula of C20H32O2 and has an active life of eight to twelve hours though its effects can be experienced up to 24 hours. The drug has an anabolic-androgenic ratio of 100-150: 30-40 and can be detected over a period of 5-6 weeks.

Mesterolone is commonly used to maintain libido off-cycle and also relatively and temporarily improving vascularity. This steroid is even used to treat male patients struggling with impotency or lack of testosterone, low libido, and erectile malfunction. It also has the ability to promote improved release of luteinizing hormone and follicle-stimulating hormone for stimulating testes so that more testosterone can be produced. This steroid is well tolerated by the liver and does not impair spermatogenesis. Proviron is recommended for treating declining physical activity and mental alertness in middle- and old-aged men. This anabolic androgenic steroid has the ability to greatly promote direct lipolysis and even promote more of free testosterone by its sex hormone binding globulin (SHBG)-binding nature. It also binds strongly the androgen receptors and SHBG. This steroid can even work to increase the activity of other steroids in an anabolic steroid cycle by displacing a higher percentage of SHBG into a free and unbound state due to its extremely high affinity for plasma binding proteins such as SHBG. Use of this drug is also useful to reduce estrogenic side effects of other steroids like water-retention, lowered sex drive, gynecomastia, etc. as Proviron prevents the formation of estrogen in the first place.

In addition to this, this steroid can also be used for treating reduced efficiency, lack of concentration, weak memory, disturbances of libido and potency, irritability, and disturbances of sleep. It is also recommended for treating depressive moods, and general vegetative complaints that are often attributed to androgen-deficiency. This anabolic steroid may also be recommended in cases of diminished potency where androgen-deficiency is not the primary cause.

Proviron can lead to a dramatic increase in the hardness and density of the muscles. It is favored by bodybuilders and power lifters during contest preparations when a lower estrogen/high androgen level is particularly sought after. Proviron also has the ability to promote the development of secondary male sex characteristics in cases of prepuberal hypogonadism and stimulate growth, development, and function of androgen-dependent target organs.

It may even be recommended for treating patients diagnosed with infertility and can be used as a substitution therapy in cases where a loss of gonadal function has occurred post-pubertal. The chances of procreation can be increased with the use of this steroid as Proviron can increase sperm count and quality. The recommended dose of Proviron for men is 25 mg three times daily. This steroid can be used for a long period of time as it is not a 17a-alkylated compound. Some athletes may use Proviron may use it in daily doses of 25-100mg per day (for men) and 40-60mg per day (for women).

Anabolic steroid abuse

Anabolic steroid abuse has been associated with a wide range of adverse side effects ranging from some that are physically unattractive, such as acne and breast development in men, to others that are life threatening, such as heart attacks and liver cancer. Most are reversible if the abuser stops taking the drugs, but some are permanent, such as voice deepening in females. Most data on the long-term effects of anabolic steroids in humans come from case reports rather than formal epidemiological studies. From the case reports, the incidence of lifethreatening effects appears to be low, but serious adverse effects may be underrecognized or underreported, especially since they may occur many years later. Data from animal studies seem to support this possibility. One study found that exposing male mice for one-fifth of their lifespan to steroid doses comparable to those taken by human athletes caused a high frequency of early deaths. 

Hormonal system: Steroid abuse disrupts the normal production of hormones in the body, causing both reversible and irreversible changes. Changes that can be reversed include reduced sperm production and shrinking of the testicles (testicular atrophy). Irreversible changes include male-pattern baldness and breast development (gynecomastia) in men. In one study of male bodybuilders, more than half had testicular atrophy and  gynecomastia. In the female body, anabolic steroids cause masculinization. Breast size and body fat decrease, the skin becomes coarse, the clitoris enlarges, and the voice deepens. Women may experience excessive growth of body hair but lose scalp hair. With continued administration of steroids, some of these effects become irreversible.

Musculoskeletal system: Rising levels of testosterone and other sex hormones normally trigger the growth spurt that occurs during puberty and adolescence and provide the signals to stop growth as well. When a child or adolescent takes anabolic steroids, the resulting artificially high sex hormone levels can prematurely signal the bones to stop growing.

Cardiovascular system: Steroid abuse has been associated with cardiovascular diseases (CVD), including heart attacks and strokes, even in athletes younger than 30. Steroids give to the development of CVD, partly by changing the levels of lipoproteins that carry cholesterol in the blood. Steroids, particularly oral steroids, increase the level of low-density lipoprotein (LDL) and reduce the level of great-density lipoprotein (HDL). Extreme LDL and low HDL levels increase the risk of atherosclerosis, a condition in which fatty substances are deposited interior arteries and disrupt blood flow. If blood is prevented from reaching the heart, the result can be a heart attack. If blood is prevented from reaching the brain, the result can be a stroke. Steroids also increase the danger that blood clots will form in blood vessels, potentially disrupting blood flow and damaging the heart muscle so that it does not pump blood effectively.

The positive effects of steroids

In most men, the use of steroids causes their testes to shrink. The drug is also known to reduce the count of sperm cells and cause total infertility to some. Steroids can also cause the hair to fall out, enlarge a man’s breasts, and affect his prostate. Teenagers who use steroids would experience halted growth. Their adolescent development will be accelerated but their skeletons will never reaching its peak. Their body grows rapidly towards puberty but the bones are left behind in the process.

Steroids have got a pretty bad rep and perhaps fairly so, they enlarge the heart, mess up our hormones and cause acne and mood disorders. However people continue to use it so there must be some positive effects of steroids. A reasoned approach then should look at both the pros and cons of these controversial substances and come to a decision that way as to whether they should be used.

Before we can appreciate the positive effects of steroids we need to understand how they work. Essentially then, steroids are either natural of synthetic compounds that help regulate various bodily functions. When we refer to steroids however we generally are referring to anabolic steroids. These are synthetic compounds that mimic the effects of anabolic and androgenic hormones such as testosterone and are known by many names including ‘juice’ and ‘roids’ and someone who is using steroids can so be said to be ‘juicing’. Anabolic steroids can be taken orally as a pill or powder or commonly via an injection which has certain advantages for the user. This makes marks along an individual’s forearms a good indicator that they may be using steroids.