How to use Cytomel and HGH in bodybuilding

Cytomel is a thyroid hormone supplement that contains liothyronine. Liothyronine is a synthetic form of the hormone T3, which is naturally produced by the thyroid gland. This medication is given when the body does not produce enough of the hormone T3 on its own, a condition known as hypothyroidism.

Human growth hormone is naturally produced by the anterior lobe of the pituitary gland. There are HGH medications available by prescription for those with kidney failure, Turner's syndrome or other diseases. HGH medications, such as somatropin, humatrope, norditropin, are only not available in pill form, they come as injections. The DEA also states, " HGH is only bio available in the injectable form. The HGH molecule is too large for absorption across the lining of the oral mucosa and the hormone is digested by the stomach before absorption can occur."

Both Cytomel and HGH are hormones that are used for medical reasons to regulate growth in individuals whose bodies do not produce enough of these hormones naturally. When a person needs the medication Cytomel, she most likely has an underactive thyroid and she will gain weight, according to the Mayo Clinic. When a person needs an HGH medication, his body is not growing enough. Cytomel is liothyronine, a man-made medication designed to mimic the action of the T3 that is naturally produced by the thyroid gland. Somatropin is an injectable form of the HGH produced by the pituitary gland.

Cytomel up-regulates the beta-2 adrenergic receptors in fat tissues. In lipolysis, or the breakdown of fat in fat tissues, the enzyme HSL (hormone sensitive lipase) plays a significant part. HSL controls the rate of lipolysis. For HSL to be activated, epinephrine and nonepinephrine (catecholomines) are necessary. These catecholomines bind to the beta-2 receptors, and thus when Cytomel up-regulates the beta-receptors, there is a corresponding increase in the ability of catecholomines to activate HSL, resulting to increased lipolysis.

This drug is likewise known to increase the UCP-3 or uncoupling protein-3. This process significantly increases lipolysis. Further, Cytomel also stimulates growth hormone (GH) production, as substantiated by several studies. And since GH is a thermogenic, it contributes to this drug’s fat-burning action. This is why when athletes are using Cytomel they find no need to use HGH. With AAS use, the suppression occurs even after the therapy is stopped, sometimes in periods of weeks or months (especially in cases of long-term use). The same thing is observed during insulin intake, whereby the pancreas (the organ responsible for insulin production) ceases its production of insulin. Such is not the case with exogenous T3 hormone therapy. Several studies have concluded that thyroid therapy does not cause prolonged suppression of thyroid normal production. Thyroid function is normalized just days after medication is discontinued. In other words, there is no thyroid shutdown due to T3 supplementation; there is only a down-regulation of thyroid output during therapy.

Side effects of this class of drug include tachycardia and atrial arrhythmia, bone resorption, and loss of lean muscle tissue. Secondary side effects include insomnia, diarrhea, and nausea. These adverse reactions are highly possible if the user takes high dosages. Notice that some of its major side effects relate to the cardiovascular system. This is because thyroid hormones have significant effects on cardiac structures (including cardiac muscles) and systems that alter cardiovascular hemodynamics. Hyperthyroidism increases virtually all cardiac functions including heart rate and contractility, diastolic relaxation, and rate of ventricular pressure development. This results to an increased cardiac output by as much as 250 percent. These physiological changes are (most likely) the consequences of an increase in the expression of ATP and a decrease in the expression of ATP’s inhibitor, phospholamban.

Another drawback of Cytomel is its catabolic ability. When Cytomel exerts this ability on stored fats, this is an asset. However, this becomes a liability when it exerts this on bones and muscles. The negative result is bone resorption and muscle wasting (mentioned above). Moreover, this drug also diminishes GH’s nitrogen retention ability (although it stimulates GH’s production, as mentioned earlier). There is consensus among Cytomel users that the dosage protocol with this drug is to ramp it up, which means you start at the lowest dosage then gradually move upward. However, there are divergent opinions on how long the ‘gradually’ part should be. There are those who say it should be every three days, and then some pharmacological studies endorse it from 1 to 2 weeks. However, the user’s tolerance level ultimately determines the time frame; that is, if the user reacts really well with Cytomel, then the dosage can gradually increase every three days. Users are advised not to ramp up and down the dosage during therapy as this causes fluctuations in hormone levels, which further results to hormonal imbalance. The more prudent practice is to taper off the dosage. The minimum daily dosage of T3 is 5mcg and the maximum is 100mcg.

Cytomel intake is not dependent on body weight or gender, but rather on the individual’s blood level. This means that females can take the same dosage volume and schedule as males.

The Benefits of GP T3 by Geneza Pharmaceuticals

GP T3 (Trijodthyronin, Cytomel) is a thyroid hormone designed and developed to treat hypothyroidism. Hypothyroidism is simply a condition where adequate thyroid hormone(s) are not being produced, commonly this can be caused by an iodine deficiency, as well as pituitary malfunction among other causes but it is a condition that is quite common. Through the use of Cytomel we can increase the amount of thyroid hormones we have in our body, most notably the Triiodothyronine hormone commonly known as T3. The Triiodothyronine hormone is responsible for many functions, most notably metabolic activity but it also plays a role in bodily growth and the heart among many others. As T3 is produced by the pituitary gland its mode of action in terms of development and release is regulated by the thyroid-stimulating hormone (TSH.) Once thyroid hormones both T3 and T4 reach a certain level in the blood production is decreased as increased levels block TSH from being released, however, once the levels fall TSH is again released and more T3 and T4 is produced. By supplementing with Cytomel we actively increase the amount of T3 in our body far beyond what natural TSH will allow.

T3 is responsible for regulating the rate in-which energy is burned in terms of both nutrient intake, as well as stored energy. By introducing Cytomel into the body, a synthetic form of the T3 hormone we increase this rate, in very simple terms Cytomel or T3 feeds off of raw energy and as levels increase more energy is needed to meet its needs. This increase in energy feeding results in producing greater metabolic activity; as stored body-fat is stored energy it begins to burn at a faster rate as the amounts of the T3 hormone increase. However, it is important to note when T3 levels increase the energy demands must be met and they will be met one way or another. This simply means both fat and muscle tissue can be used as this energy source; while fat will be the primary focus, if adequate measures are not taken when consuming Cytomel muscle tissue will be burned as the Cytomel will get what it needs by any means possible and will not discriminate.


With a simple understanding of Cytomel and the T3 hormone understanding its benefits should come quite easily. By taking Cytomel we increase the amount of T3 in our body, by increasing the amount of T3 in our body we increase metabolic activity; by increasing metabolic activity we increase the rate in-which we burn fat. When we look at it in its most simplistic terms it is just that, rather simple; however, to fully understand the benefits of Cytomel we must understand the full effects of the T3 hormone which are quite vast and affect many various areas. While these affects are vast we are only largely concerned with how they affect metabolic activity, however, it’s effects can stretch to even the heart as increased levels of the T3 hormone increase cardiac output

By taking GP T3 (Cytomel) we greatly increase protein efficiency, however, we also increase the rate in-which protein is broken down. Due to this fact adequate amounts of protein must be taken in but this is good news as even though we require more than normal each gram is now being utilized to a far greater degree. Further and this is of the greatest importance, when we take GP T3 (Trijodthyronin, Cytomel) we increase the rate in-which glucose is metabolized by increasing the rate in-which glycogen is broken down. The faster this occurs the sooner the body is required to rely on stored body-fat for an energy source. Further and of equal importance, by taking GP T3 we increase the rate in-which cholesterol is broken down, all of these things greatly aid in increasing the rate of lipolysis.

The Side-Effects:
As is with all medications GP T3 (Cytomel) does carry with it potential negative side-effects, however many of the side-effects commonly associated with this medication are of little truth but some do exist. The blatant obvious negative effect is undoubtedly the loss of muscle tissue; as many performance enhancing athletes use Cytomel in an aid to lose body-fat they do so on a calorie restricted diet, because of this low consumption of calories, if adequate amounts are not in place muscle tissue will be burned. For this reason, a performance enhancing athlete will never take Cytomel without anabolic steroids, ignoring this rule will assuredly result in the loss of a vast amount of lean tissue. Beyond this possible negative side-effect others do exist but they prove to be very individualistic, dose dependent and in many cases very rare. Possible side-effects include most commonly, headaches, insomnia and excess sweating. Many women who use GP T3 (Trijodthyronin, Cytomel) may also find their menstrual cycles disrupted, however, this is often to be expected when body-fat becomes extremely low.
We have established that as a performance enhancing athlete GP T3 is to only be used in conjunction with anabolic steroids and never alone as use alone will in-fact result in a loss of muscle tissue. With this in mind the next question is when is the best time to use? It should go without saying that during cutting cycles such as a competitive bodybuilding cycle is the best time to use this medication and common practice is to use GP T3 the final 6 weeks of competition to get rid of that last bit of fat; however, it can be successfully used for the entire duration of a diet but one will need to keep an eye on tissue loss if this path is taken. For most a cycle of GP T3 (Cytomel) that is in the 6-8 week range will prove to be all the Cytomel they’ll ever need. As for the amounts, generally 25mcg per day is a good place to start with increases of 12.5mcg being applied as needed. This protocol includes Cytomel cycles for both men and women, however both will necessarily keep the dose as low as possible and only increase as needed. Most men can increase their dose safely to 150mcg per day while women will necessarily keep a maximum dose at 100mcg per day. In either case, learn to listen to your body, learn how to accurately observe your body and the effects and if you do you’ll find your Cytomel use to be more enjoyable and effective. There is a final note that will prove to provide a great benefit in thyroid recovery after use is discontinued, easing into recovery is far more beneficial. There is no need to gradually ramp down but rather simply drop your dose down to the original starting point of 25mcg every day and hold for approximately two weeks. By following this method you will ensure your thyroid begins production sooner than later.