Viagra - How it Stimulates and Enhances Erections

Many men suffer from erectile dysfunction (ED) - the inability to achieve and sustain an erection long enough to have enjoyable and fulfilling sex. For a variety of reasons ED is most common in men over 45. The sex drive is often lowered even further in older men who are taking medications of various kinds.

Most of us assume the sex drive gradually diminishes as we get older, so we are prepared to accept ED as a natural condition. But the fact is, the inability for many men to sustain an erection may be more the result of treatable physical conditions rather than an actual loss of sex drive.

Until the antediluvian 1980s most people - including most trained urologists - expropriated that ED was basically a unbalanced or psychological problem. But in 1983 at a award to the American Urological Connection, Dr. Giles Brindley demonstrated that a penis could be made set up by injecting it with the deaden phentolamine. In a public picketing, he used his own penis to away the point. Brindley had discovered that the penis could be made construct by relaxing the normally constricted blood vessels peerless into it. Once the blood vessels are blas, they let in more blood and the penis inflates something like a balloon to deportment an erection. So scale it came to be accepted that ED is the upshot of physical changes in the mature male - not especially mental or psychological conditions.

Viagra - Controlling the Penile Valve Phentolamine - the medication used by Dr. Brindley to blow the whistle on himself a public erection - started to be hardened with some ascendancy in the 80's and 90's, but there are two problems with phentolamine. Senior, it is not selective enough to quarry only the penis, so its effects on other parts of the portion are unpredictable. And second, the erections it creates are not brought on by sexy stimulation. You can get an erection any old shilly-shally with phentolamine, and you order continue to have one until the influence of the drug wears off. Viagra was the essential drug that overcame these two problems. (It was introduced in 1998 by the Pfizer comrades. The active ingredient in Viagra is sildenafil citrate.) Viagra does not realize find time by relaxing the blood vessels of the penis. A substitute alternatively it enhances the natural processes that contain place when a man is sexually stimulated.

It does this by controlling what we dominion call the "Softeners" - the chemicals in the society designed to make the penis go matt after an erection. It works something like this. When a man is sexually stimulated his knowledge sends signals that trigger the origination of chemicals that rest the blood vessels in the penis. Over of these as "Hardeners". As the blood vessels are easygoing by the production of Hardeners, blood deluge increases and the penis goes found. But nature has also designed a way for the erection to piecemeal subside. At the same perpetually as Hardeners are being produced to ease the blood vessels, the assemblage is also producing Softeners to tell down and neutralize the Hardeners. These are an enzyme known as phosphodiesterase (PDE5).

As long as the sexually stimulated male is producing more Hardeners than Softeners, the penis will remain erect. But as soon as the production of Hardeners starts to go down, the Softeners will get the upper hand, and the erection will start to fizzle.

It is now generally assumed that ED is caused by an imbalance of Hardeners and Softeners. The body is either not producing enough Hardeners, or too many Softeners. Either way, the result is the inability to sustain an erection.

What Viagra does is block the production of Softeners. This allows the Hardeners to build up in the blood vessels of the penis and create hard, sustained erections.

The attractiveness of the process is that nothing happens without physical stimulation. Viagra does not win the place of stimulation. Rather than, it simply lets the fitting chemicals created by reproductive stimulation do their pressurize. After sex, when the acumen is no longer creating Hardeners, the erection subsides clearly. And when the effects of Viagra show off - normally after 4 or 5 hours - the ordinary processes are restored to the way they were prior to taking the drug. Of without a doubt, as with any drug, there are budding side effects. Viagra should not be captivated if you are taking any nitrate-based remedy, including nitroglycerin or if you are on any blood tension or heart medication, as combining Viagra with these drugs can source a severe drop in blood influence. Also, if you have any liver or kidney problems it is not recommended that you bamboozle Viagra.