Move over, Viagra! Researchers in Italy report that an ancient Chinese herbal remedy known as "horny goat weed" shows potential in lab studies as source for new future drugs to treat erectile dysfunction (ED). The study, which provides scientific evidence supporting the herb's well-known use as a natural aphrodisiac, is scheduled for the October 24 issue of ACS' Journal of Natural Products, a monthly publication.
In the new study, Mario Dell'Agli and colleagues point out that Viagra (sildenafil) and several other prescription drugs are now available for ED, or male impotence. ED affects an estimated 18 million men in the United States alone. Studies show, however, that these drugs may cause side effects such as headache, facial flushing, stomach upset, and visual disturbances.
To find better treatments, the scientists studied herbal extracts reputed to improve sexual performance. Scientists exposed the substances to an enzyme that controls blood flow to the penis and whose inhibition results in an erection. Of the extracts tested, "horny goat weed" was the most potent inhibitor of the enzyme. By chemical modification of icariin, the active ingredient purified from the extract, the scientists obtained a derivative with activity similar to Viagra and a potential for fewer side effects because it targeted the protein more precisely than sildenafil.
About ViagraViagra is a prescription medication indicated for the treatment of ED. Viagra is available only from health care providers and should always be used in accordance with its approved labeling. Viagra is contraindicated in patients who use nitrates in any form at any time.
Patients should discuss their general health status with their doctors to ensure that they are healthy enough to engage in sexual activity. If patients experience pain, nausea, or any other discomfort during sex, or an erection that lasts longer than four hours, they should seek medical help.
The most common side effects of Viagra(reg) (sildenafil citrate) are headache, facial flushing and upset stomach. Less commonly, bluish vision, blurred vision or sensitivity to light may briefly occur.
Patients with recent serious cardiovascular events, hypertension or controlled hypertension or retinues pigmentation did not participate in pre-approval clinical trials. In these patients, physicians should prescribe Viagra with caution. The use of Viagra offers no protection against sexually transmitted diseases, including human immunodeficiency virus (HIV).
Discovered and developed by Pfizer, Viagra is the breakthrough oral treatment for erectile dysfunction that is found to be effective and well tolerated in more than 130 completed and ongoing clinical studies. Viagra has been approved by regulatory authorities in more than 123 countries around the world and is among the most widely prescribed medications, with more than 130 million prescriptions written for 23 million men worldwide.
Pfizer Inc discovers, develops, manufactures and markets leading prescription medications for humans and animals and many of the world's best-known consumer products.
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